Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.59 |
| ▸ | NOS1 | P29475 | 3/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3064844 | 0.81 | NOS1 (0.63) | NOS1HSP90AA1IDO1CDK2PLK4 | |
| SCHEMBL20540332 | 0.77 | PIK3CD (0.64) | PIK3CDPIK3CBPIK3CGDHFRAHR | |
| SCHEMBL19346097 | 0.76 | PIK3CD (0.45) | PIK3CDPIK3CBNOS1PIK3CGDHFR | |
| SCHEMBL28736122 | 0.76 | PIK3CD (0.49) | PIK3CDPIK3CBNOS1HSP90AA1IDO1 | |
| SCHEMBL29592536 | 0.76 | PIK3CD (0.49) | PIK3CDPIK3CBNOS1HSP90AA1IDO1 | |
| SCHEMBL20078834 | 0.76 | PIK3CD (0.44) | PIK3CDPIK3CBNOS1PIK3CGDHFR | |
| SCHEMBL22013889 | 0.74 | PIK3CD (0.53) | PIK3CDPIK3CBPIK3CGDHFRKDM4E | |
| SCHEMBL21324055 | 0.72 | NOS1 (0.45) | NOS1HSP90AA1IDO1CDK2PLK4 | |
| SCHEMBL20866826 | 0.71 | ADRA2A (0.49) | PIK3CBNOS1HSP90AA1IDO1CDK2 | |
| SCHEMBL4752843 | 0.69 | NOS1 (0.53) | NOS1HSP90AA1IDO1CDK2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331673-A1 | COMPOSITION OF COMPOUNDS THAT MODULATE CELL METABOLISM AND METHODS OF USE | CRESCENTA BIOSCIENCES (US) | 2023-10-19 | — | — | US | disclosed |
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331673-A1 | COMPOSITION OF COMPOUNDS THAT MODULATE CELL METABOLISM AND METHODS OF USE | FABP4, FABP1, FABP3 | PIK3CD 4831/4885PIK3CB 4679/4885NOS1 3839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.