Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NPY1R | P25929 | 1/20 | 0.58 |
| ▸ | NPY2R | P49146 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20682737 | 0.86 | L3MBTL1 (1.00) | L3MBTL1HTTMAPTNPY1RNPY2R | |
| SCHEMBL15709049 | 0.86 | L3MBTL1 (1.00) | L3MBTL1HTTMAPTNPY1RNPY2R | |
| SCHEMBL8637458 | 0.84 | L3MBTL1 (0.70) | L3MBTL1HTTMAPTNPY1RNPY2R | |
| SCHEMBL9700301 | 0.79 | L3MBTL1 (0.84) | L3MBTL1HTTMAPTNPY1RNPY2R | |
| SCHEMBL20854834 | 0.76 | L3MBTL1 (0.77) | L3MBTL1HTTMAPTNPY1RNPY2R | |
| SCHEMBL7366723 | 0.74 | L3MBTL1 (0.71) | L3MBTL1HTTMAPTNPY1RNPY2R | |
| SCHEMBL9563286 | 0.74 | CYP2D6 (0.70) | L3MBTL1HTTMAPTCYP2D6CYP2C19 | |
| SCHEMBL27870149 | 0.73 | CYP2D6 (0.69) | L3MBTL1HTTCYP2D6CYP2C19CYP1A2 | |
| SCHEMBL6221394 | 0.73 | NPC1 (0.66) | L3MBTL1HTTMAPTCYP2D6CYP2C19 | |
| SCHEMBL8610306 | 0.72 | MAPT (0.70) | L3MBTL1HTTMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190099453-A1 | MEDICAMENT FOR LIVER REGENERATION AND FOR TREATMENT OF LIVER FAILURE | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2019-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190099453-A1 | MEDICAMENT FOR LIVER REGENERATION AND FOR TREATMENT OF LIVER FAILURE | PYGL, HNF4A, ATF1 | L3MBTL1 407/4885HTT 4857/4885MAPT 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.