SCHEMBL20873281

SCHEMBL20873281

C#CCOCCOCCOCCOc1ccc(N2CCN(C[C@H]3OC(O)[C@H](O)[C@@H](O)[C@H]3O)CC2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 2/20 0.43
▸ SLC5A1 P13866 1/20 0.43
▸ MAPT P10636 2/20 0.37
▸ LMNA P02545 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ HRH3 Q9Y5N1 3/20 0.34
▸ DRD3 P35462 6/20 0.33
▸ DRD2 P14416 5/20 0.33
▸ HTR1A P08908 4/20 0.33
▸ HTR2A P28223 4/20 0.33
▸ DRD4 P21917 2/20 0.33
▸ DRD5 P21918 2/20 0.33
▸ DRD1 P21728 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ TMEM97 Q5BJF2 3/20 0.33
▸ SIGMAR1 Q99720 3/20 0.33
▸ HRH1 P35367 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21148624 1.00 SLC5A2 (0.43) SLC5A2SLC5A1MAPTLMNASMN1; SMN2
SCHEMBL21148625 1.00 SLC5A2 (0.43) SLC5A2SLC5A1MAPTLMNASMN1; SMN2
SCHEMBL24138061 0.76 MAPT (0.48) MAPTLMNASMN1; SMN2DRD4ALDH1A1
SCHEMBL20873314 0.76 MAPT (0.48) MAPTLMNASMN1; SMN2DRD4ALDH1A1
SCHEMBL21149325 0.76 ALDH1A1 (0.35) MAPTLMNASMN1; SMN2L3MBTL1HRH3
SCHEMBL20873246 0.75 DRD4 (0.44) MAPTLMNASMN1; SMN2DRD3DRD2
SCHEMBL20873286 0.74 DRD4 (0.45) MAPTSMN1; SMN2DRD3DRD2HTR1A
SCHEMBL26993128 0.71 ADRB1 (0.48) HRH3SIGMAR1HRH1KCNH2
SCHEMBL21112885 0.70 DRD2 (0.35) MAPTLMNASMN1; SMN2L3MBTL1HRH3
SCHEMBL26993127 0.69 MAPT (0.50) MAPTLMNASMN1; SMN2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210401946-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-12-30 — — US disclosed
US-20210401946-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-12-30 — — US disclosed
US-20210401947-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-12-30 — — US disclosed
US-20210401947-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-12-30 — — US disclosed
US-11090364-B2 Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein SANOFI (FR) 2021-08-17 — — US disclosed
US-11090364-B2 Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein SANOFI (FR) 2021-08-17 — — US disclosed
US-20190209656-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2019-07-11 — — US disclosed
US-20190209656-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2019-07-11 — — US disclosed
EP-3463480-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN Sanofi (FR) 2019-04-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11090364-B2 Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein GPR119, SLC2A8, SLC2A4 SLC5A2 11/4885SLC5A1 12/4885MAPT 3717/4885
US-20190209656-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 SLC5A2 11/4885SLC5A1 12/4885MAPT 3717/4885
US-20210401946-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 SLC5A2 11/4885SLC5A1 12/4885MAPT 3717/4885
US-20210401947-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 SLC5A2 11/4885SLC5A1 12/4885MAPT 3717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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