Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 3/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | CMA1 | P23946 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20740123 | 1.00 | CTSL (0.50) | CTSLCASP1CA2CA1CTSG | |
| SCHEMBL23967346 | 0.89 | GAA (0.54) | CTSLCASP1CA2CA1TDP1 | |
| SCHEMBL19463858 | 0.87 | CA2 (0.52) | CTSLCA2CA1CTSGCTRB1 | |
| SCHEMBL4896298 | 0.86 | NPC1 (0.53) | CTSLCASP1TDP1LMNAHSD17B10 | |
| SCHEMBL697053 | 0.84 | CA2 (0.65) | CA2CA1ACETMPRSS15GAA | |
| SCHEMBL697052 | 0.84 | CA2 (0.65) | CA2CA1ACETMPRSS15GAA | |
| SCHEMBL712931 | 0.84 | CA2 (0.65) | CA2CA1ACETMPRSS15GAA | |
| SCHEMBL29159682 | 0.83 | CA2 (0.63) | CA2CA1ACETMPRSS15GAA | |
| SCHEMBL9301907 | 0.83 | CASP1 (0.46) | CASP1TDP1GAAMAPT | |
| SCHEMBL13868571 | 0.81 | GAA (0.53) | CTSLCA2CA1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12145130-B2 | Multimodal adsorption medium with multimodal ligands, method for the preparation and use thereof | SARTORIUS STEDIM BIOTECH GMBH (DE) | 2024-11-19 | — | — | US | disclosed |
| US-20220055015-A1 | MULTIMODAL ADSORPTION MEDIUM WITH MULTIMODAL LIGANDS, METHOD FOR THE PREPARATION AND USE THEREOF | SARTORIUS STEDIM BIOTECH GMBH (DE) | 2022-02-24 | — | — | US | disclosed |
| US-20190105632-A1 | MULTIMODAL ADSORPTION MEDIUM WITH MULTIMODAL LIGANDS, METHOD FOR THE PREPARATION AND USE THEREOF | SARTORIUS STEDIM BIOTECH GMBH (DE) | 2019-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12145130-B2 | Multimodal adsorption medium with multimodal ligands, method for the preparation and use thereof | NEFM, ADM2, IGFBP4 | CTSL 1150/4885CASP1 4833/4885CA2 543/4885 |
| US-20190105632-A1 | MULTIMODAL ADSORPTION MEDIUM WITH MULTIMODAL LIGANDS, METHOD FOR THE PREPARATION AND USE THEREOF | NEFM, ADM2, IGFBP4 | CTSL 1150/4885CASP1 4833/4885CA2 543/4885 |
| US-20220055015-A1 | MULTIMODAL ADSORPTION MEDIUM WITH MULTIMODAL LIGANDS, METHOD FOR THE PREPARATION AND USE THEREOF | NEFM, ADM2, IGFBP4 | CTSL 1150/4885CASP1 4833/4885CA2 543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.