Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.65 |
| ▸ | CA1 | P00915 | 4/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697052 | 1.00 | CA2 (0.65) | CA2CA1CASP3GAAMAPT | |
| SCHEMBL697053 | 1.00 | CA2 (0.65) | CA2CA1CASP3GAAMAPT | |
| SCHEMBL29159682 | 0.98 | CA2 (0.63) | CA2CA1CASP3GAAMAPT | |
| SCHEMBL28334970 | 0.86 | CA2 (0.50) | CA2CA1ACEPTPN1SLC1A2 | |
| SCHEMBL9829896 | 0.86 | CA2 (0.66) | CA2CA1CASP3PTPN1TMPRSS15 | |
| SCHEMBL5280601 | 0.86 | CA2 (0.68) | CA2CA1ACEPTPN1SLC1A2 | |
| SCHEMBL9829891 | 0.86 | CA2 (0.66) | CA2CA1CASP3PTPN1TMPRSS15 | |
| SCHEMBL5191250 | 0.86 | CA2 (0.68) | CA2CA1ACEPTPN1SLC1A2 | |
| Phenylalanine SCHEMBL10413087 | 0.85 | SLC7A5 (0.59) | CA2CA1GAAMAPTACE | |
| SCHEMBL20875154 | 0.84 | CTSL (0.50) | CA2CA1CASP3GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116735753-A | Detection method of benzoyl-L-aspartic acid dimethyl ester enantiomer | 上海司太立制药有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-8586638-B2 | Parakeratosis inhibitor and skin preparation for external use | SHISEIDO COMPANY, LTD (JP) | 2013-11-19 | — | — | US | disclosed |
| US-20120253064-A1 | PARAKERATOSIS INHIBITOR AND SKIN PREPARATION FOR EXTERNAL USE | SHISEIDO COMPANY, LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| EP-2491980-A2 | Parakeratosis inhibitor and skin preparation for external use | SHISEIDO COMPANY LIMITED (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-2491981-A2 | Parakeratosis inhibitor and external composition for skin | SHISEIDO COMPANY LIMITED (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20120053243-A1 | PARAKERATOSIS INHIBITOR AND SKIN PREPARATION FOR EXTERNAL USE | SHISEIDO COMPANY, LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| CN-102274130-A | Application of n- benzene sulfonyl-l-glutamic acid or saline thereof | — | 2011-12-14 | — | — | CN | disclosed |
| CN-102266269-A | Parakeratosis inhibitor and external composition for skin | — | 2011-12-07 | — | — | CN | disclosed |
| CN-1886114-B | Parakeratosis inhibitor and composition for external use on skin | SHISEIDO CO LTD | 2011-08-10 | — | — | CN | disclosed |
| US-7569690-B2 | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| CN-100360510-C | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINECHEMICALS CO LTD (JP) | 2008-01-09 | — | — | CN | disclosed |
| US-20070225380-A1 | Parakeratosis Inhibitor and Skin Preparation for External use | SHISEIDO COMPANY LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
| CN-1886114-A | Parakeratosis inhibitor and composition for external use on skin | SHISEIDO CO LTD (JP) | 2006-12-27 | — | — | CN | disclosed |
| EP-1688126-A1 | PARAKERATOSIS INHIBITOR AND EXTERNAL COMPOSITION FOR SKIN | SHISEIDO COMPANY LIMITED (JP) | 2006-08-09 | — | — | EP | disclosed |
| US-20060161003-A1 | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2006-07-20 | — | — | US | disclosed |
| CN-1681797-A | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINECHEMICALS CO LTD (JP) | 2005-10-12 | — | — | CN | disclosed |
| EP-1548010-A1 | PROCESS FOR PRODUCING OXYCARBONYL-SUBSTITUTED PIPERAZINE DERIVATIVE | Toray Fine Chemicals Co., Ltd. (JP) | 2005-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053243-A1 | PARAKERATOSIS INHIBITOR AND SKIN PREPARATION FOR EXTERNAL USE | CUTA, HPN, DNPEP | CA2 2319/4885CA1 3325/4885CASP3 2101/4885 |
| US-20120253064-A1 | PARAKERATOSIS INHIBITOR AND SKIN PREPARATION FOR EXTERNAL USE | CUTA, HPN, PRSS1 | CA2 2770/4885CA1 4382/4885CASP3 3322/4885 |
| US-20060161003-A1 | Process for producing oxycarbonyl-substituted piperazine derivative | DHPS, AQP4, OGFOD1 | CA2 2603/4885CA1 3233/4885CASP3 516/4885 |
| US-20070225380-A1 | Parakeratosis Inhibitor and Skin Preparation for External use | CUTA, HPN, DNPEP | CA2 2319/4885CA1 3325/4885CASP3 2101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.