Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 5/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18924326 | 0.80 | KDM4E (0.40) | ALDH1A1GAAL3MBTL1ARKDM4E | |
| SCHEMBL2054606 | 0.78 | ALDH1A1 (0.41) | ALDH1A1GAAL3MBTL1MAPK1NR3C2 | |
| SCHEMBL19863918 | 0.77 | UHRF1 (0.42) | ARCNR2CNR1ESR1 | |
| SCHEMBL21719254 | 0.76 | RECQL (0.39) | ARCNR2CNR1 | |
| SCHEMBL21718459 | 0.76 | AR (0.48) | ARCNR2CNR1MAPK1ESR1 | |
| SCHEMBL23879473 | 0.76 | CNR2 (0.38) | ALDH1A1L3MBTL1ARCNR2CNR1 | |
| SCHEMBL18431456 | 0.76 | NOS2 (0.52) | ARCNR2CNR1PRKCQPRKCA | |
| SCHEMBL19592834 | 0.76 | MKNK1 (0.47) | ARCNR2CNR1ESR1ADRB2 | |
| SCHEMBL27099646 | 0.75 | RAB9A (0.34) | ALDH1A1GAAPRKCAPRKCDPRKD1 | |
| SCHEMBL18765834 | 0.74 | ALDH1A1 (0.43) | ALDH1A1GAAL3MBTL1ARNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10253027-B2 | Aryl lactam kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253027-B2 | Aryl lactam kinase inhibitors | AAK1, ADCK1, ANKK1 | ALDH1A1 2563/4885GAA 1957/4885L3MBTL1 2143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.