Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26741483 | 0.82 | — | — | |
| SCHEMBL26829294 | 0.78 | HRH3 (0.44) | RAB9ALMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL13658049 | 0.76 | RAB9A (0.43) | RAB9ALMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL20877697 | 0.75 | ALDH1A1 (0.36) | LMNAGAAPRKCAPRKCDPRKD1 | |
| SCHEMBL2054606 | 0.74 | ALDH1A1 (0.41) | RAB9ALMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL18610039 | 0.73 | RAB9A (0.35) | RAB9ALMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL24124013 | 0.73 | RAB9A (0.43) | RAB9ALMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL12019745 | 0.72 | HCAR3 (0.46) | RAB9ALMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL22621603 | 0.72 | SYK (0.42) | RAB9ALMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL12293195 | 0.72 | HCAR3 (0.53) | RAB9ALMNAMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912682-B2 | Isoindolinone compounds | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912682-B2 | Isoindolinone compounds | CYP4F2, AOC2, AOC3 | RAB9A 3175/4885LMNA 1164/4885MAPT 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.