Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20879776 | 0.87 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNASMN1; SMN2MAPT | |
| SCHEMBL14960573 | 0.86 | ALDH1A1 (0.48) | ALDH1A1HPGDTSHRKDM4EHTT | |
| SCHEMBL13060130 | 0.86 | ALDH1A1 (0.48) | ALDH1A1HPGDTSHRKDM4EHTT | |
| SCHEMBL18532596 | 0.86 | ALDH1A1 (0.48) | ALDH1A1HPGDTSHRKDM4EHTT | |
| SCHEMBL18790113 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL18532609 | 0.86 | TRPM8 (0.44) | ALDH1A1TSHRHTTLMNASMN1; SMN2 | |
| SCHEMBL24016940 | 0.85 | UBE2M (0.52) | ALDH1A1TSHRKDM4EHTTLMNA | |
| SCHEMBL18532607 | 0.84 | KMT2A (0.53) | ALDH1A1HPGDTSHRKDM4ELMNA | |
| SCHEMBL24016937 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HPGDTSHRHTTLMNA | |
| SCHEMBL12176000 | 0.84 | ALDH1A1 (0.45) | ALDH1A1HPGDTSHRKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3078658-B1 | C5AR ANTAGONISTS | CHEMOCENTRYX INC (US) | 2019-04-10 | — | — | EP | disclosed |