Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 4/20 | 0.52 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790113 | 0.91 | ALDH1A1 (0.44) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL18790110 | 0.87 | UBE2M (0.51) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL13326991 | 0.87 | UBE2M (0.51) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL18532611 | 0.87 | HCRTR1 (0.41) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL14960484 | 0.87 | UBE2M (0.51) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL25132778 | 0.85 | EPHX2 (0.43) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL20879820 | 0.85 | LMNA (0.56) | KDM4EMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL20879814 | 0.85 | ALDH1A1 (0.53) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL12176202 | 0.85 | UBE2M (0.46) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL20879776 | 0.84 | ALDH1A1 (0.45) | UBE2MDCUN1D1ALDH1A1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508477-B1 | C5AR ANTAGONISTS | CHEMOCENTRYX INC (US) | 2021-11-10 | — | — | EP | disclosed |