Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12900871 | 1.00 | KMT2A (0.38) | KMT2AGAAEPHX1ALDH1A1TSHR | |
| SCHEMBL9887646 | 0.89 | L3MBTL1 (0.34) | ALDH1A1MAPTTP53 | |
| SCHEMBL14980975 | 0.89 | L3MBTL1 (0.34) | ALDH1A1MAPTTP53 | |
| SCHEMBL9887647 | 0.89 | L3MBTL1 (0.34) | ALDH1A1MAPTTP53 | |
| SCHEMBL23020573 | 0.88 | L3MBTL1 (0.37) | ALDH1A1MAPTTP53 | |
| SCHEMBL21974892 | 0.88 | L3MBTL1 (0.37) | ALDH1A1MAPTTP53 | |
| SCHEMBL24098133 | 0.84 | SIGMAR1 (0.41) | EPHX1ALDH1A1KDM4EDUSP3PTPN11 | |
| SCHEMBL23955948 | 0.84 | SIGMAR1 (0.36) | KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL23955947 | 0.84 | SIGMAR1 (0.36) | KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL9887637 | 0.84 | SIGMAR1 (0.36) | KMT2AALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922267-A1 | PEGYLATED RECOMBINANT HUMAN GROWTH HORMONE COMPOUNDS | ASCENDIS PHARMA ENDOCRINOLOGY DIVISION A/S (DK) | 2021-12-15 | — | — | EP | disclosed |
| EP-2459220-B1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | ASCENDIS PHARMA AS (DK) | 2020-09-09 | — | — | EP | disclosed |
| EP-2237799-B1 | PRODRUG COMPRISING A SELF-CLEAVABLE LINKER | ASCENDIS PHARMA AS (DK) | 2019-04-10 | — | — | EP | disclosed |