Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9887637 | 1.00 | SIGMAR1 (0.36) | SIGMAR1CHRM5CHRM3RAD52PADI1 | |
| SCHEMBL23955948 | 1.00 | SIGMAR1 (0.36) | SIGMAR1CHRM5CHRM3RAD52PADI1 | |
| SCHEMBL9887646 | 0.89 | L3MBTL1 (0.34) | SIGMAR1CHRM5CHRM3ALDH1A1MAPT | |
| SCHEMBL14980975 | 0.89 | L3MBTL1 (0.34) | SIGMAR1CHRM5CHRM3ALDH1A1MAPT | |
| SCHEMBL9887647 | 0.89 | L3MBTL1 (0.34) | SIGMAR1CHRM5CHRM3ALDH1A1MAPT | |
| SCHEMBL21974892 | 0.88 | L3MBTL1 (0.37) | SIGMAR1CHRM5CHRM3ALDH1A1MAPT | |
| SCHEMBL23020573 | 0.88 | L3MBTL1 (0.37) | SIGMAR1CHRM5CHRM3ALDH1A1MAPT | |
| SCHEMBL20879918 | 0.86 | CHRM5 (0.36) | SIGMAR1CHRM5CHRM3RAD52PADI1 | |
| SCHEMBL24098133 | 0.84 | SIGMAR1 (0.41) | SIGMAR1ALDH1A1 | |
| SCHEMBL20879964 | 0.84 | KMT2A (0.38) | ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596805-B1 | Prodrug comprising a drug-linker conjugate | ASCENDIS PHARMA AS (DK) | 2021-10-27 | — | — | EP | disclosed |