SCHEMBL2089321

SCHEMBL2089321

CC(C)(C)OC(=O)NC(C)(C)C(=O)NCC(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
APLNR P35414 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA12 O43570 2/20 0.34
CA9 Q16790 2/20 0.34
CA7 P43166 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
CTSK P43235 3/20 0.32
CACNA1H O95180 1/20 0.32
CACNA1B Q00975 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4202727 0.81 TDP1 (0.48) TDP1MAOAMAOBMEN1GAA
SCHEMBL15792134 0.78 MEN1 (0.33) MEN1GAAKMT2ALMNAPOLB
SCHEMBL17212001 0.77 CA2 (0.50) TDP1MAOAMAOBMEN1GAA
SCHEMBL62352 0.77 TDP1 (0.42) TDP1MAOAMAOBMEN1GAA
SCHEMBL17211116 0.77 TDP1 (0.42) TDP1MAOAMAOBMEN1GAA
SCHEMBL28918296 0.75 APLNR (0.40) TDP1MEN1GAAKMT2AAPLNR
SCHEMBL22991709 0.74 KDM4C (0.41) MEN1KMT2ALMNAPOLBPGK1
SCHEMBL1289840 0.74 TDP1 (0.42) TDP1MAOAMAOBMEN1GAA
SCHEMBL15792091 0.74 LMNA (0.49) TDP1MAOAMAOBMEN1GAA
SCHEMBL4449244 0.74 TDP1 (0.36) TDP1MEN1GAAKMT2AAPLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025022883-A1 METHOD FOR PRODUCING AMIDE COMPOUND 日本曹達株式会社 2025-01-30 WO disclosed
EP-3778563-B1 PHENOXYUREA COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO (JP) 2024-05-29 EP disclosed
US-11044911-B2 Phenoxyurea compound and pest control agent NIPPON SODA CO., LTD. (JP) 2021-06-29 US disclosed
US-20210051960-A1 PHENOXYUREA COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2021-02-25 US disclosed
WO-2019198592-A1 PHENOXYUREA COMPOUND AND PEST CONTROL AGENT 日本曹達株式会社 2019-10-17 WO disclosed
EP-3491922-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO Dow AgroSciences LLC (US) 2019-06-05 EP disclosed
US-20170158675-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2017-06-08 US disclosed
US-9622477-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-04-18 US disclosed
US-9538756-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-01-10 US disclosed
US-20160044925-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-02-18 US disclosed
EP-2532667-A1 Deazapurines useful as inhibitors of janus kinases Vertex Pharmaceuticals Incorporated (US) 2012-12-12 EP disclosed
EP-1931674-B1 DEAZAPURINES USEFUL AS INHIBITORS OF JANUS KINASES VERTEX PHARMA (US) 2012-12-12 EP disclosed
US-20120165307-A1 AZAINDOLES USEFUL AS INHIBITORS OF JANUS KINASES VERTEX PHARMACEUTICALS INCORPORATED (US) 2012-06-28 US disclosed
US-8163917-B2 Azaindoles useful as inhibitors of Janus kinases VERTEX PHARMACEUTICALS INCORPORATED (US) 2012-04-24 US disclosed
US-20100311743-A1 Azaindoles Useful as Inhibitors of Janus Kinases VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-12-09 US disclosed
US-7767816-B2 for treating proliferative disorders, cardiac disorders, neurodegenerative disorders, autoimmune disorders, conditions associated with organ transplantation, inflammatory disorders, and/or immunologically mediated disorders VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-08-03 US disclosed
EP-1973911-A2 AZAINDOLES USEFUL AS INHIBITORS OF JANUS KINASES Vertex Pharmaceuticals, Inc. (US) 2008-10-01 EP disclosed
US-20070207995-A1 Deazapurines useful as inhibitors of Janus kinases VERTEX PHARMACEUTICALS INCORPORATED 2007-09-06 US disclosed
US-20070203142-A1 for treating proliferative disorders, cardiac disorders, neurodegenerative disorders, autoimmune disorders, conditions associated with organ transplantation, inflammatory disorders, and/or immunologically mediated disorders VERTEX PHARMACEUTICALS INCORPORATED 2007-08-30 US disclosed
WO-2007084557-A2 AZAINDOLES USEFUL AS INHIBITORS OF JANUS KINASES VERTEX PHARMACEUTICALS INCORPORATED (US) 2007-07-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203142-A1 for treating proliferative disorders, cardiac disorders, neurodegenerative disorders, autoimmune disorders, conditions associated with organ transplantation, inflammatory disorders, and/or immunologically mediated disorders JAK1, JAK3, MYLK2 TDP1 406/4885MAOA 3304/4885MAOB 2627/4885
US-20120165307-A1 AZAINDOLES USEFUL AS INHIBITORS OF JANUS KINASES JAK3, JAK1, JAK2 TDP1 1359/4885MAOA 1649/4885MAOB 1816/4885
US-20100311743-A1 Azaindoles Useful as Inhibitors of Janus Kinases JAK3, JAK1, JAK2 TDP1 1359/4885MAOA 1649/4885MAOB 1816/4885
US-20210051960-A1 PHENOXYUREA COMPOUND AND PEST CONTROL AGENT H1-0, H1-4, H1-3 TDP1 3466/4885MAOA 3375/4885MAOB 3077/4885
US-20160044925-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS TDP1 2276/4885MAOA 699/4885MAOB 1013/4885
US-20170158675-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS TDP1 2276/4885MAOA 699/4885MAOB 1013/4885
US-20070207995-A1 Deazapurines useful as inhibitors of Janus kinases JAK1, JAK3, JAK2 TDP1 539/4885MAOA 3049/4885MAOB 2722/4885
US-11044911-B2 Phenoxyurea compound and pest control agent H1-0, H1-4, H1-3 TDP1 3466/4885MAOA 3375/4885MAOB 3077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.