SCHEMBL20904164

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25346919	0.98	CYP3A4 (0.48)	CYP3A4TPSAB1TPSD1TPSG1IDO1
	SCHEMBL18705411	0.97	CYP3A4 (0.43)	CYP3A4TPSAB1TPSD1TPSG1IDO1
	SCHEMBL22946820	0.94	HPGD (0.41)	CYP3A4IDO1HDAC3HDAC4HDAC1
	SCHEMBL22021517	0.93	EPHX2 (0.41)	CYP3A4HDAC3HDAC4HDAC1HDAC7
	SCHEMBL10177563	0.89	HTT (0.47)	CYP3A4IDO1HDAC3HDAC4HDAC1
	SCHEMBL29959208	0.88	HTT (0.49)	CYP3A4IDO1HDAC3HDAC4HDAC1
	SCHEMBL18879474	0.88	MAPT (0.48)	CYP3A4IDO1HDAC3HDAC4HDAC1
	SCHEMBL25752594	0.88	HPGD (0.48)	CYP3A4HDAC3HDAC4HDAC1HDAC7
	SCHEMBL27250873	0.87	HDAC8 (0.41)	HDAC8MAPTL3MBTL1SYKEPHX2
	SCHEMBL17599919	0.87	CYP3A4 (0.59)	CYP3A4TPSAB1TPSD1TPSG1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.