Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 2/20 | 0.46 |
| ▸ | METAP1 | P53582 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20677806 | 0.87 | KMT2A (0.56) | KMT2APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL11436852 | 0.80 | PIN1 (0.59) | KMT2APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL29258829 | 0.80 | TCF4 (0.59) | METAP2METAP1CBFB | |
| SCHEMBL481951 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HTTRAB9AKDM4EMAPT | |
| SCHEMBL1663444 | 0.80 | MEN1 (0.54) | KMT2APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL20883960 | 0.77 | SCN10A (0.52) | KMT2APOLBCYP1A2NPC1RAB9A | |
| SCHEMBL20884005 | 0.77 | MCHR1 (0.46) | KMT2APOLBALDH1A1CYP1A2NPC1 | |
| SCHEMBL266609 | 0.76 | ALDH1A1 (0.66) | KMT2APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL29727934 | 0.76 | ALDH1A1 (0.66) | KMT2APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL358399 | 0.75 | LMNA (0.62) | KMT2APOLBALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074979-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | GIRAFPHARMA, LLC (US) | 2019-04-18 | — | — | WO | disclosed |