Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23917929 | 0.83 | LMNA (0.45) | HTR2ALMNAMAPTALDH1A1GPR84 | |
| SCHEMBL27338595 | 0.80 | HTR2A (0.45) | HTR2AHTR2CHTR2BLMNAMAPT | |
| SCHEMBL3353333 | 0.78 | HTR6 (0.46) | HTR2AHTR2CHTR2BLMNAMAPT | |
| SCHEMBL23604756 | 0.75 | LMNA (0.40) | HTR2ALMNAMAPTALDH1A1HTR1D | |
| SCHEMBL13537350 | 0.75 | HTR2A (0.41) | HTR2AHTR2CHTR2BLMNAMAPT | |
| SCHEMBL10261961 | 0.74 | GPR84 (0.67) | HTR2AHTR2CHTR2BLMNAMAPT | |
| SCHEMBL23393948 | 0.74 | SCN9A (0.36) | LMNAMAPTALDH1A1HTR6HTT | |
| SCHEMBL17992597 | 0.74 | IDO1 (0.37) | LMNAMAPTALDH1A1HTT | |
| SCHEMBL17660621 | 0.74 | LMNA (0.42) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL23490154 | 0.72 | ALDH1A1 (0.43) | LMNAMAPTALDH1A1HTR1DSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074979-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | GIRAFPHARMA, LLC (US) | 2019-04-18 | — | — | WO | disclosed |