Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353042 | 0.87 | HTR6 (0.47) | HTR6HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL27338595 | 0.82 | HTR2A (0.45) | HTR6HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL3349651 | 0.79 | HTR6 (0.41) | HTR6HTR2ASLC6A4 | |
| SCHEMBL20910199 | 0.78 | HTR2A (0.42) | HTR6HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL13537350 | 0.77 | HTR2A (0.41) | HTR6HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL9060813 | 0.77 | HTR2A (0.43) | HTR6HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL10261961 | 0.76 | GPR84 (0.67) | HTR6HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL3354155 | 0.75 | CDK2 (0.47) | HTR2AHTR2CHTR2BLMNASMN1; SMN2 | |
| Iodomethane SCHEMBL4607667 | 0.73 | GPR84 (0.62) | HTR6HTR2AHTR2CHTR2BGPR84 | |
| SCHEMBL2075509 | 0.73 | HTR2A (0.44) | HTR6HTR2AADRB2HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |