SCHEMBL20913009

SCHEMBL20913009

COC(=O)C(=O)C1CCCOC1=O

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 3/20 0.35
HPGD P15428 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2707058 0.81 FKBP1A (0.36) FKBP1ACYP1A2
SCHEMBL16516708 0.81 ALDH1A1 (0.40) FKBP1AHPGDCYP1A2CYP2C9CYP2C19
SCHEMBL20930306 0.77 ALDH1A1 (0.33) FKBP1A
SCHEMBL535757 0.75 FKBP1A (0.36) FKBP1AMAPK1
SCHEMBL7614074 0.74 MAPK1 (0.45) CYP1A2MAPK1
SCHEMBL2057726 0.74 MMP3 (0.36) FKBP1A
SCHEMBL2058089 0.74 MMP3 (0.36) FKBP1A
SCHEMBL2057725 0.74 MMP3 (0.36) FKBP1A
SCHEMBL1005232 0.73 MAPK1 (0.51) CYP1A2MAPK1
SCHEMBL10567776 0.72 FKBP1A (0.34) FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4252755-A2 THERAPEUTIC COMPOUNDS C4x Discovery Limited (GB) 2023-10-04 EP disclosed
EP-3870578-B1 THERAPEUTIC COMPOUNDS C4X DISCOVERY LTD (GB) 2023-08-16 EP disclosed
US-20220002286-A1 THERAPEUTIC COMPOUNDS C4X DISCOVERY LIMITED (GB) 2022-01-06 US disclosed
CN-112996785-A Therapeutic compounds 希四克斯探索有限公司 2021-06-18 CN disclosed
EP-3473098-A1 COMPOSITION FOR REGULATING PLANT GROWTH, METHOD FOR TREATING PLANTS THEREWITH, AND ACTIVE INGREDIENT THEREOF Gorbunov, Sergei Valeryevich (RU) 2019-04-24 EP disclosed
EP-3473098-A1 COMPOSITION FOR REGULATING PLANT GROWTH, METHOD FOR TREATING PLANTS THEREWITH, AND ACTIVE INGREDIENT THEREOF Gorbunov, Sergei Valeryevich (RU) 2019-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220002286-A1 THERAPEUTIC COMPOUNDS NFE2L2, KEAP1, NQO1 FKBP1A 928/4885HPGD 174/4885CYP1A2 527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.