SCHEMBL20915674

SCHEMBL20915674

C=CC(=O)OC(C)Cc1c2ccccc2c(CC(C)OC(=O)C=C)c2c(Oc3c(Oc4ccccc4)ccc4c(CC(C)OC(=O)C=C)c5ccccc5c(CC(C)OC(=O)C=C)c34)c(Oc3ccccc3)ccc12

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
POLB P06746 2/20 0.32
LMNA P02545 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
RECQL P46063 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
FFAR1 O14842 1/20 0.31
TGM2 P21980 1/20 0.30
SCN9A Q15858 1/20 0.30
BRD4 O60885 1/20 0.30
TTR P02766 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20915342 0.87 KDM4E (0.37) POLBLMNAL3MBTL1KDM4EMAPT
SCHEMBL20915633 0.85
SCHEMBL20915474 0.84
SCHEMBL20915557 0.82 TUBB4A (0.31) THRBL3MBTL1HTT
SCHEMBL20915772 0.81 THRB (0.33) THRBL3MBTL1
SCHEMBL20915529 0.80 LMNA (0.36) POLBLMNAL3MBTL1KDM4EMAPT
SCHEMBL20915439 0.78 THRB (0.49) THRBHTTSMN1; SMN2TGM2TTR
SCHEMBL20915775 0.76 THRB (0.47) THRBSMN1; SMN2TGM2
SCHEMBL20915627 0.72 KMT2A (0.32) LMNAKDM4EMAPTTTR
SCHEMBL20915437 0.70 LTA4H (0.39) POLBLMNAL3MBTL1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11149103-B2 Photopolymerization sensitizer composition and photopolymerizable composition comprising the same KAWASAKI KASEI CHEMICALS LTD. (JP) 2021-10-19 US disclosed
US-20190119426-A1 PHOTOPOLYMERIZATION SENSITIZER COMPOSITION AND PHOTOPOLYMERIZABLE COMPOSITION COMPRISING THE SAME KAWASAKI KASEI CHEMICALS LTD. (JP) 2019-04-25 US disclosed