Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19506428 | 0.87 | PDE2A (0.48) | PDE2AALDH1A1TSHRLMNASLC7A5 | |
| SCHEMBL14233628 | 0.85 | PDE2A (0.56) | PDE2AALDH1A1TSHRLMNASLC7A5 | |
| SCHEMBL12318715 | 0.85 | PDE2A (0.56) | PDE2AALDH1A1TSHRLMNASLC7A5 | |
| SCHEMBL2093547 | 0.84 | PDE2A (0.47) | PDE2AALDH1A1TSHRLMNASLC7A5 | |
| SCHEMBL1044972 | 0.84 | PDE2A (0.47) | PDE2AALDH1A1TSHRLMNASLC7A5 | |
| SCHEMBL25749775 | 0.84 | PDE2A (0.50) | PDE2AALDH1A1TSHRLMNASLC7A5 | |
| SCHEMBL27600859 | 0.83 | PDE2A (0.50) | PDE2AALDH1A1TSHRLMNASLC7A5 | |
| SCHEMBL1042393 | 0.81 | PDE2A (0.45) | PDE2AALDH1A1SLC7A5HDAC3HDAC1 | |
| SCHEMBL1042394 | 0.81 | PDE2A (0.45) | PDE2AALDH1A1LMNASLC7A5HDAC3 | |
| SCHEMBL2093775 | 0.81 | PDE2A (0.45) | PDE2AALDH1A1TSHRLMNASLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873288-B2 | Inhibitors for soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-16 | — | — | US | disclosed |
| US-20230157287-A1 | PESTICIDAL COMPOUNDS | BASF SE (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20210155601-A1 | INHIBITORS FOR SOLUBLE EPOXIDE HYDROLASE (SEH) AND FATTY ACID AMIDE HYDROLASE (FAAH) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-05-27 | — | — | US | disclosed |
| US-20210070713-A1 | PESTICIDAL COMPOUNDS | BASF SE (DE) | 2021-03-11 | — | — | US | disclosed |
| US-10858338-B2 | Inhibitors for soluble epoxide hydrolase (SEH) and fatty acid amide hydrolase (FAAH) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-08 | — | — | US | disclosed |
| US-20200270311-A1 | SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE | ST JUDE CHILDREN'S HOSPITAL (US) | 2020-08-27 | — | — | US | disclosed |
| US-10696713-B2 | Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof | ENANTA PHARMACEUTICALS, INC. (US) | 2020-06-30 | — | — | US | disclosed |
| US-10428025-B2 | Antifungal compound process | Mycovia Pharmaceuticals, Inc. (US) | 2019-10-01 | — | — | US | disclosed |
| US-10407392-B2 | Antifungal compound process | Mycovia Pharmaceuticals, Inc. (US) | 2019-09-10 | — | — | US | disclosed |
| US-10399943-B2 | Antifungal compound process | Mycovia Pharmaceuticals, Inc. (US) | 2019-09-03 | — | — | US | disclosed |
| US-20170144990-A1 | ANTIFUNGAL COMPOUND PROCESS | Mycovia Pharmaceuticals, Inc. | 2017-05-25 | — | — | US | disclosed |
| US-20170081285-A1 | ANTIFUNGAL COMPOUND PROCESS | Mycovia Pharmaceuticals, Inc. | 2017-03-23 | — | — | US | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| CN-100584823-C | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL CO | 2010-01-27 | — | — | CN | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| CN-100376549-C | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL CO (JP) | 2008-03-26 | — | — | CN | disclosed |
| CN-101033200-A | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL CO (JP) | 2007-09-12 | — | — | CN | disclosed |
| CN-1639114-A | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL CO (JP) | 2005-07-13 | — | — | CN | disclosed |
| CN-1524071-A | Malononitrile compounds and their use as pesticides | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-08-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696713-B2 | Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof | GPBAR1, NR1H4, SLC10A1 | PDE2A 982/4885ALDH1A1 2372/4885TSHR 236/4885 |
| US-20200270311-A1 | SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE | CLPP, DNPEP, PEPD | PDE2A 1738/4885ALDH1A1 4416/4885TSHR 3864/4885 |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | PDE2A 3649/4885ALDH1A1 412/4885TSHR 162/4885 |
| US-20170144990-A1 | ANTIFUNGAL COMPOUND PROCESS | ERG28, DPM1, CYP51A1 | PDE2A 3677/4885ALDH1A1 1891/4885TSHR 4755/4885 |
| US-20230157287-A1 | PESTICIDAL COMPOUNDS | PNMT, CAT, DDT | PDE2A 242/4885ALDH1A1 1917/4885TSHR 2805/4885 |
| US-11873288-B2 | Inhibitors for soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH) | FAAH, FAAH2, EPHX2 | PDE2A 2169/4885ALDH1A1 261/4885TSHR 2275/4885 |
| US-10407392-B2 | Antifungal compound process | ERG28, DPM1, CYP51A1 | PDE2A 3677/4885ALDH1A1 1891/4885TSHR 4755/4885 |
| US-20210155601-A1 | INHIBITORS FOR SOLUBLE EPOXIDE HYDROLASE (SEH) AND FATTY ACID AMIDE HYDROLASE (FAAH) | FAAH, FAAH2, EPHX2 | PDE2A 2169/4885ALDH1A1 261/4885TSHR 2275/4885 |
| US-10399943-B2 | Antifungal compound process | ERG28, DPM1, CYP51A1 | PDE2A 3677/4885ALDH1A1 1891/4885TSHR 4755/4885 |
| US-20210070713-A1 | PESTICIDAL COMPOUNDS | CAT, NIT2, PNMT | PDE2A 301/4885ALDH1A1 1368/4885TSHR 2952/4885 |
| US-10858338-B2 | Inhibitors for soluble epoxide hydrolase (SEH) and fatty acid amide hydrolase (FAAH) | FAAH, FAAH2, EPHX2 | PDE2A 2169/4885ALDH1A1 261/4885TSHR 2275/4885 |
| US-10428025-B2 | Antifungal compound process | ERG28, DPM1, CYP51A1 | PDE2A 3677/4885ALDH1A1 1891/4885TSHR 4755/4885 |
| US-20170081285-A1 | ANTIFUNGAL COMPOUND PROCESS | ERG28, DPM1, CYP51A1 | PDE2A 3677/4885ALDH1A1 1891/4885TSHR 4755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.