SCHEMBL20961997

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20968012	0.87	MAPT (0.55)	MCL1ACMSDHTTDHODHPIN1
	SCHEMBL20968004	0.83	MCL1 (0.51)	MCL1ACMSDMAPTPTPN1KDM4E
	SCHEMBL20961992	0.82	BRD4 (0.45)	MCL1ACMSDMAPTGAAGPR35
	SCHEMBL20968005	0.82	MCL1 (0.63)	MCL1ACMSDMAPTKDM4EMEN1
	SCHEMBL26606612	0.79	MCL1 (0.45)	MCL1ACMSDMAPTKDM4EMEN1
	SCHEMBL26609300	0.76	BRD4 (0.40)	HTTDHODHL3MBTL1MAPTGAA
	SCHEMBL12128796	0.75	PTPRC (0.46)	DHODHL3MBTL1PTPRCPTPN1KDM4E
	SCHEMBL20962011	0.74	GAA (0.47)	MCL1ACMSDHTTPIN1MAPT
	SCHEMBL9196740	0.72	GABRA1 (0.48)	MCL1HTTPIN1GAA
	SCHEMBL1957953	0.71	SMN1; SMN2 (0.56)	HTTL3MBTL1MAPTKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.