SCHEMBL20968005

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20968004	0.85	MCL1 (0.51)	MCL1ACMSDMAPTKDM4EMEN1
	SCHEMBL20961998	0.85	MCL1 (0.64)	MCL1ACMSDMAPTXDHSLC22A12
	SCHEMBL20968056	0.83	MCL1 (0.60)	MCL1ACMSDMAPTCYP2C9CYP2C19
	SCHEMBL20961997	0.82	MCL1 (0.44)	MCL1ACMSDMAPTKDM4EMEN1
	SCHEMBL26606612	0.81	MCL1 (0.45)	MCL1ACMSDMAPTCYP2C9KDM4E
	SCHEMBL20961992	0.80	BRD4 (0.45)	MCL1ACMSDMAPTCYP2C9CYP2C19
	SCHEMBL2534281	0.77	MCL1 (1.00)	MCL1ACMSDXDHSLC22A12MEN1
	SCHEMBL5494830	0.74	MCL1 (0.71)	MCL1ACMSDKDM4EMEN1POLB
	SCHEMBL23759473	0.73	NR4A1 (0.52)	MCL1ACMSDMAPTCYP2C9KDM4E
	SCHEMBL3799705	0.72	HPRT1 (0.48)	KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.