SCHEMBL20962001

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20962003	0.88	HPGD (0.54)	ALDH1A1LMNAHPGDHTTCYP1A2
	SCHEMBL20961992	0.87	BRD4 (0.45)	ALDH1A1LMNAHPGDCYP1A2PGR
	SCHEMBL20961994	0.86	GSTA1 (0.53)	ALDH1A1LMNAHPGDKDM4EMAPT
	SCHEMBL20968012	0.84	MAPT (0.55)	ALDH1A1LMNAHPGDHTTCYP1A2
	SCHEMBL20961998	0.80	MCL1 (0.64)	LMNAHPGDKDM4EMAPTHSD17B10
	SCHEMBL3902536	0.78	LMNA (0.77)	ALDH1A1LMNAHPGDHTTCYP1A2
	SCHEMBL20968004	0.74	MCL1 (0.51)	ALDH1A1LMNAHPGDKDM4EMAPT
	SCHEMBL28023333	0.74	KMT2A (0.61)	MAPTCYP2C8RAB9AKMT2AGAA
	SCHEMBL2790754	0.74	SERPINE1 (0.54)	ALDH1A1LMNAHPGDHTTCYP2D6
	SCHEMBL10621564	0.73	GSTA1 (0.74)	LMNAHPGDKDM4EMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.