Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.73 |
| ▸ | RARB | P10826 | 2/20 | 0.73 |
| ▸ | RARG | P13631 | 2/20 | 0.73 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | ATP4A | P20648 | 2/20 | 0.55 |
| ▸ | ATP4B | P51164 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12618487 | 0.94 | RARA (0.65) | RARARARBRARGAPEX1ATP4A | |
| SCHEMBL11452930 | 0.93 | RARA (0.69) | RARARARBRARGAPEX1ATP4A | |
| SCHEMBL11456645 | 0.89 | APEX1 (0.72) | RARARARBRARGAPEX1ATP4A | |
| SCHEMBL2760388 | 0.89 | APEX1 (0.72) | RARARARBRARGAPEX1ATP4A | |
| SCHEMBL96684 | 0.85 | RARA (0.61) | RARARARBRARGAPEX1ATP4A | |
| SCHEMBL11460952 | 0.84 | RARA (0.56) | RARARARBRARGKDM4EALDH1A1 | |
| SCHEMBL13533549 | 0.82 | RARA (0.54) | RARARARBRARGAPEX1ATP4A | |
| SCHEMBL26136461 | 0.82 | RARA (0.61) | RARARARBRARGAPEX1ATP4A | |
| SCHEMBL427731 | 0.81 | SMN1; SMN2 (0.59) | RARARARBRARGKDM4EALDH1A1 | |
| SCHEMBL2093741 | 0.81 | ALDH1A1 (0.59) | RARARARBRARGALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153703-A | Method of controlling insects and acarids with certain aryl-substituted thiazoles | UNIROYAL, INC. (US) | 1979-05-08 | — | — | US | claimed |
| CN-111315727-B | Benzothiazole compounds and methods of treating neurodegenerative diseases using the same | 第一生物治疗股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| US-11659766-B2 | Organic semiconductor material for electron transport | DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2023-05-23 | — | — | US | disclosed |
| US-11659766-B2 | Organic semiconductor material for electron transport | DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2023-05-23 | — | — | US | disclosed |
| US-11345688-B2 | Compound, preparing method therefor, and organic light emitting element comprising same | DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-05-31 | — | — | US | disclosed |
| US-20190189933-A1 | ORGANIC SEMICONDUCTOR MATERIAL FOR ELECTRON TRANSPORT | DAEGU GYEONGBUK INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2019-06-20 | — | — | US | disclosed |
| EP-1957073-B1 | MEDICINAL DRUG | OTSUKA PHARMA CO LTD (JP) | 2014-04-23 | — | — | EP | disclosed |
| US-8551999-B2 | Heterocyclic compound and pharmaceutical composition thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-10-08 | — | — | US | disclosed |
| EP-2612858-A1 | STAT3/5 activation inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-07-10 | — | — | EP | disclosed |
| US-20120322807-A1 | STAT3/5 ACTIVATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. | 2012-12-20 | — | — | US | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| WO-2008044667-A1 | STAT3/5 ACTIVATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-04-17 | — | — | WO | disclosed |
| US-20070270422-A1 | Aromatic Compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| WO-2007066784-A2 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | WO | disclosed |
| EP-1773797-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-04-18 | — | — | EP | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2006014012-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-02-09 | — | — | WO | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| US-4197306-A | CONTROL OF INSECTS AND ACARIDS | UNIROYAL, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153703-A | Method of controlling insects and acarids with certain aryl-substituted thiazoles | UNIROYAL, INC. (US) | 1979-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | RARA 121/4885RARB 90/4885RARG 174/4885 |
| US-20120322807-A1 | STAT3/5 ACTIVATION INHIBITOR | STAT3, JAK2, STAT1 | RARA 787/4885RARB 620/4885RARG 862/4885 |
| US-20070270422-A1 | Aromatic Compounds | COL1A1, COL2A1, COL14A1 | RARA 456/4885RARB 523/4885RARG 556/4885 |
| US-11345688-B2 | Compound, preparing method therefor, and organic light emitting element comprising same | CYP4F11, CYP4A11, WEE2 | RARA 2394/4885RARB 2882/4885RARG 2655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.