Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12219413 | 0.87 | DPP4 (0.33) | SHBGALDH1A1KDM4EGAA | |
| SCHEMBL12218816 | 0.87 | DPP4 (0.33) | SHBGALDH1A1KDM4EGAA | |
| SCHEMBL14671260 | 0.87 | DPP4 (0.33) | SHBGALDH1A1KDM4EGAA | |
| SCHEMBL12422222 | 0.79 | PHGDH (0.35) | ALDH1A1KDM4EHRH3MEN1CYP2D6 | |
| SCHEMBL19656271 | 0.79 | — | — | |
| SCHEMBL14788270 | 0.77 | HSD11B1 (0.36) | HRH3CYP2D6 | |
| SCHEMBL14164304 | 0.77 | — | — | |
| SCHEMBL12346658 | 0.77 | GNAI3 (0.38) | SPHK1HTT | |
| SCHEMBL12487354 | 0.77 | — | — | |
| SCHEMBL21121000 | 0.77 | HRH3 (0.38) | ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339184-B2 | Antibacterial compounds, compositions thereof, and methods using same | THE ROCKEFELLER UNIVERSITY (US) | 2022-05-24 | — | — | US | disclosed |
| US-20210024562-A1 | ANTIBACTERIAL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS USING SAME | THE ROCKEFELLER UNIVERSITY | 2021-01-28 | — | — | US | disclosed |
| US-10759750-B2 | Beta lactams as modulators of glutamate uptake and methods for use thereof | Temple University—Of the Commonwealth System of Higher Education (US) | 2020-09-01 | — | — | US | disclosed |
| US-10457692-B2 | Pyrimido-diazepinone compounds and methods of treating disorders | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-10-29 | — | — | US | disclosed |
| US-20190127323-A1 | Novel Beta Lactams as Modulators of Glutamate Uptake and Methods for Use Thereof | Temple University--of the Commonwealth System of Higher Education | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759750-B2 | Beta lactams as modulators of glutamate uptake and methods for use thereof | SLC1A2, SLC1A1, SLC7A11 | SHBG 1014/4885ALDH1A1 885/4885KDM4E 1619/4885 |
| US-11339184-B2 | Antibacterial compounds, compositions thereof, and methods using same | CLPP, MPO, SPOUT1 | SHBG 3951/4885ALDH1A1 3433/4885KDM4E 4054/4885 |
| US-10457692-B2 | Pyrimido-diazepinone compounds and methods of treating disorders | BRSK2, GRK3, BRSK1 | SHBG 4789/4885ALDH1A1 4309/4885KDM4E 3369/4885 |
| US-20190127323-A1 | Novel Beta Lactams as Modulators of Glutamate Uptake and Methods for Use Thereof | SLC1A2, SLC1A1, SLC7A11 | SHBG 1599/4885ALDH1A1 1035/4885KDM4E 1876/4885 |
| US-20210024562-A1 | ANTIBACTERIAL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS USING SAME | CLPP, MPO, SPOUT1 | SHBG 3951/4885ALDH1A1 3433/4885KDM4E 4054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.