SCHEMBL20969583

SCHEMBL20969583

CCC(N)c1ccc(OC)c(C(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 2/20 0.41
ADRA1A P35348 2/20 0.41
CYP2D6 P10635 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
GFER P55789 1/20 0.41
ACHE P22303 3/20 0.41
BCHE P06276 1/20 0.41
TYR P14679 1/20 0.41
SLC6A4 P31645 1/20 0.41
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41
THRB P10828 1/20 0.40
RORC P51449 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
PPARG P37231 1/20 0.39
PPARD Q03181 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14032377 0.85 ACHE (0.51) GAAACHESLC6A4MEN1KMT2A
Hydrochloric Acid SCHEMBL5117534 0.84 ACHE (0.50) GAAACHESLC6A4MEN1BLM
SCHEMBL7099805 0.83 ALDH1A1 (0.50) GAAACHEMAPK1
SCHEMBL16865875 0.83 ALDH1A1 (0.50) GAAACHEMAPK1
SCHEMBL16865878 0.83 ALDH1A1 (0.50) GAAACHEMAPK1
SCHEMBL6423584 0.83 ALDH1A1 (0.50) GAAACHEMAPK1
SCHEMBL10360993 0.82 CYP2D6 (0.46) ADRA2AADRA1ACYP2D6POLBGAA
SCHEMBL739698 0.81 HDAC4 (0.48) ADRA2AADRA1ACYP2D6POLBGAA
SCHEMBL10362112 0.81 TAS1R3 (0.44) CYP2D6ACHESLC6A4PPARGPPARD
SCHEMBL20969582 0.79 ADRA2A (0.46) ADRA2AADRA1ACYP2D6POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3483149-B1 BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME YUHAN CORP (KR) 2021-01-13 EP disclosed
US-10383859-B2 Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same YUHAN CORPORATION (KR) 2019-08-20 US disclosed
US-20190142809-A1 Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same YUHAN CORPORATION (KR) 2019-05-16 US disclosed
EP-3483149-A1 BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME Yuhan Corporation (KR) 2019-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142809-A1 Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same ILK, SBDS, BDKRB1 ADRA2A 3691/4885ADRA1A 3339/4885CYP2D6 3325/4885
US-10383859-B2 Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same ILK, SBDS, BDKRB1 ADRA2A 3691/4885ADRA1A 3339/4885CYP2D6 3325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.