SCHEMBL20970969

SCHEMBL20970969

COc1cc(CCNCc2cccc(O)c2)c(OC)cc1Br

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 20/20 1.00
HTR2C P28335 9/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30033696 0.86 HTR2A (1.00) HTR2AHTR2C
SCHEMBL25398226 0.86 HTR2A (1.00) HTR2AHTR2C
SCHEMBL3455690 0.82 BCHE (0.70) HTR2AHTR2C
SCHEMBL27173123 0.81 HTR2A (0.67) HTR2AHTR2C
SCHEMBL29633105 0.80 HTR2A (0.79) HTR2AHTR2C
SCHEMBL25245620 0.80 HTR2A (0.79) HTR2AHTR2C
SCHEMBL30033916 0.80 HTR2A (1.00) HTR2AHTR2C
SCHEMBL17287281 0.78 HTR2A (1.00) HTR2AHTR2C
SCHEMBL29528608 0.78 HTR2A (1.00) HTR2AHTR2C
SCHEMBL25392368 0.78 HTR2A (1.00) HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME KULEON LLC (US) 2026-04-02 US disclosed
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-03 US disclosed
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS KULEON LLC (US) 2025-11-06 US disclosed
US-20250289817-A1 SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2025-09-18 US disclosed
US-12344582-B2 Mixed serotonin 5-HT2A/2C receptor agonists and methods for treating pain and depression Kuleon, LLC (US) 2025-07-01 US disclosed
US-20250145638-A1 Serotonin Receptor Agonists and Methods of Making and Using the Same KULEON LLC (US) 2025-05-08 US disclosed
US-20250091991-A1 MIXED SEROTONIN 5-HT2A/2C RECEPTOR AGONISTS AND METHODS FOR TREATING PAIN AND DEPRESSION Kuleon, LLC (US) 2025-03-20 US disclosed
US-12187678-B2 Methods of treating psychological disorders through the administration of serotonin 5-HT2C receptor modulators Kuleon, LLC (US) 2025-01-07 US disclosed
US-20240294538-A1 Serotonin Receptor Agonists and Methods of Making and Using the Same KULEON LLC (US) 2024-09-05 US disclosed
EP-4384172-A1 HALLUCINOGENIC AND NON-HALLUCINOGENIC SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME Kuleon LLC (US) 2024-06-19 EP disclosed
US-20240124397-A1 METHODS OF TREATING PSYCHOLOGICAL DISORDERS THROUGH THE ADMINISTRATION OF SEROTONIN 5-HT2C RECEPTOR MODULATORS Kuleon, LLC (US) 2024-04-18 US disclosed
WO-2024077203-A1 SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2024-04-11 WO disclosed
WO-2023225043-A1 TRICYCLIC AND TETRACYCLIC SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-11-23 WO disclosed
US-11780807-B2 Benzoselenophene, benzothiophene, and benzofuran analogs and methods of modulating the serotonin 5-HT2C receptor Kuleon, LLC (US) 2023-10-10 US disclosed
US-20230257346-A1 BENZOSELENOPHENE AND SELENOPHENOPYRIDINE ANALOGS AND METHODS OF MODULATING THE SEROTONIN 5-HT2C RECEPTOR Kuleon, LLC (US) 2023-08-17 US disclosed
WO-2023122135-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-06-29 WO disclosed
WO-2023122320-A1 POLYPODAL SEROTONERGIC COMPOUNDS AND PRODRUGS OF SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS KULEON LLC (US) 2023-06-29 WO disclosed
WO-2023023298-A1 HALLUCINOGENIC AND NON-HALLUCINOGENIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PSILOSTERICS, LLC (US) 2023-02-23 WO disclosed
WO-2023018864-A1 HALLUCINOGENIC AND NON-HALLUCINOGENIC SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME PSILOSTERICS, LLC (US) 2023-02-16 WO disclosed
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CAAMTECH, INC. 2019-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CNR1, CNR2, HTR5A HTR2A 6/4885HTR2C 8/4885
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME HTR2C, HTR7, HTR6 HTR2A 6/4885HTR2C 1/4885
US-20250289817-A1 SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME HTR5A, HTR1A, HTR3A HTR2A 5/4885HTR2C 11/4885
US-12187678-B2 Methods of treating psychological disorders through the administration of serotonin 5-HT2C receptor modulators HTR2C, HTR2A, HTR3B HTR2A 2/4885HTR2C 1/4885
US-11780807-B2 Benzoselenophene, benzothiophene, and benzofuran analogs and methods of modulating the serotonin 5-HT2C receptor HTR2C, HTR2A, HTR3C HTR2A 2/4885HTR2C 1/4885
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS HTR2A, HTR2C, HTR3A HTR2A 1/4885HTR2C 2/4885
US-20240294538-A1 Serotonin Receptor Agonists and Methods of Making and Using the Same HTR1A, HTR7, HTR3A HTR2A 9/4885HTR2C 10/4885
US-20240124397-A1 METHODS OF TREATING PSYCHOLOGICAL DISORDERS THROUGH THE ADMINISTRATION OF SEROTONIN 5-HT2C RECEPTOR MODULATORS HTR2C, HTR2A, HTR3B HTR2A 2/4885HTR2C 1/4885
US-20230257346-A1 BENZOSELENOPHENE AND SELENOPHENOPYRIDINE ANALOGS AND METHODS OF MODULATING THE SEROTONIN 5-HT2C RECEPTOR HTR2C, HTR2A, HTR3B HTR2A 2/4885HTR2C 1/4885
US-12344582-B2 Mixed serotonin 5-HT2A/2C receptor agonists and methods for treating pain and depression HTR2A, HTR2C, HTR3A HTR2A 1/4885HTR2C 2/4885
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same HTR5A, HTR1A, HTR1D HTR2A 16/4885HTR2C 7/4885
US-20250091991-A1 MIXED SEROTONIN 5-HT2A/2C RECEPTOR AGONISTS AND METHODS FOR TREATING PAIN AND DEPRESSION HTR2A, HTR2C, HTR3A HTR2A 1/4885HTR2C 2/4885
US-20250145638-A1 Serotonin Receptor Agonists and Methods of Making and Using the Same HTR1A, HTR3A, HTR5A HTR2A 5/4885HTR2C 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.