Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 20/20 | 0.49 |
| ▸ | CASP6 | P55212 | 18/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 18/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23251434 | 0.92 | CASP3 (0.44) | CASP3CASP6CASP8 | |
| SCHEMBL20827575 | 0.89 | CASP3 (0.56) | CASP3CASP6CASP8 | |
| SCHEMBL20980797 | 0.89 | CASP3 (0.53) | CASP3CASP6CASP8 | |
| SCHEMBL20981231 | 0.86 | CTSK (0.40) | CASP3CASP6CASP8 | |
| SCHEMBL26623257 | 0.77 | CASP1 (0.62) | CASP3CASP6CASP8 | |
| SCHEMBL26623260 | 0.77 | CASP1 (0.62) | CASP3CASP6CASP8 | |
| SCHEMBL78881 | 0.77 | CASP3 (0.51) | CASP3CASP6CASP8 | |
| SCHEMBL78880 | 0.77 | CASP3 (0.51) | CASP3CASP6CASP8 | |
| SCHEMBL22862226 | 0.77 | KLK7 (0.54) | CASP3CASP6CASP8 | |
| SCHEMBL20980796 | 0.75 | CTSK (0.42) | CASP3CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190135733-A1 | CASPASE INHIBITOR AND PHARMACEUTICAL COMPOSITION, USE AND THERAPEUTIC METHOD THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190135733-A1 | CASPASE INHIBITOR AND PHARMACEUTICAL COMPOSITION, USE AND THERAPEUTIC METHOD THEREOF | CASP1, CASP14, CASP2 | CASP3 7/4885CASP6 9/4885CASP8 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.