Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2076291 | 0.74 | TDP1 (0.33) | TDP1 | |
| SCHEMBL27545600 | 0.73 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL4407497 | 0.73 | — | — | |
| SCHEMBL8486133 | 0.69 | — | — | |
| SCHEMBL20985445 | 0.67 | SLC6A2 (0.32) | — | |
| SCHEMBL27529850 | 0.67 | — | — | |
| SCHEMBL4447065 | 0.67 | — | — | |
| SCHEMBL27934672 | 0.67 | — | — | |
| SCHEMBL7810060 | 0.65 | THRB (0.32) | — | |
| SCHEMBL8664070 | 0.64 | ALDH1A1 (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3394080-B1 | LIPID-LINKED PRODRUGS | UNIV BRITISH COLUMBIA (CA) | 2023-06-07 | — | — | EP | disclosed |
| US-10780174-B2 | Lipid-linked prodrugs | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2020-09-22 | — | — | US | disclosed |
| US-20190151458-A1 | Lipid-Linked Prodrugs | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10780174-B2 | Lipid-linked prodrugs | SGMS2, SGMS1, LIPA | LMNA 2162/4885L3MBTL1 1011/4885TDP1 2331/4885 |
| US-20190151458-A1 | Lipid-Linked Prodrugs | SGMS2, SGMS1, LIPA | LMNA 2162/4885L3MBTL1 1011/4885TDP1 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.