SCHEMBL209877

SCHEMBL209877

O=C1CC(=O)N(CCc2ccccc2)C(=O)N1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.72
MAPT P10636 6/20 0.72
CYP3A4 P08684 1/20 0.72
CYP2C9 P11712 1/20 0.72
PKM P14618 1/20 0.72
CYP2C19 P33261 1/20 0.72
KMT2A Q03164 8/20 0.65
MEN1 O00255 7/20 0.65
HSD17B10 Q99714 4/20 0.65
GAA P10253 3/20 0.65
L3MBTL1 Q9Y468 2/20 0.65
HTT P42858 2/20 0.65
USP2 O75604 1/20 0.65
APAF1 O14727 1/20 0.55
CASP1 P29466 1/20 0.55
RAB9A P51151 1/20 0.55
BLM P54132 1/20 0.55
CASP7 P55210 1/20 0.55
GSK3A P49840 2/20 0.51
GSK3B P49841 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium SCHEMBL11515942 0.98 ALDH1A1 (0.70) ALDH1A1MAPTCYP3A4CYP2C9PKM
Methoxymethane SCHEMBL27770059 0.94 ALDH1A1 (0.65) ALDH1A1MAPTCYP3A4CYP2C9PKM
Acetaldehyde SCHEMBL27922507 0.93 MAPT (0.63) ALDH1A1MAPTCYP3A4CYP2C9PKM
SCHEMBL5586057 0.88 MAPT (0.57) ALDH1A1MAPTCYP3A4CYP2C9PKM
SCHEMBL18344445 0.88 MAPT (0.57) ALDH1A1MAPTCYP3A4CYP2C9PKM
SCHEMBL21359707 0.86 KMT2A (0.73) ALDH1A1MAPTCYP3A4CYP2C9PKM
SCHEMBL28778523 0.85 MAPT (0.55) ALDH1A1MAPTCYP3A4CYP2C9PKM
SCHEMBL18183374 0.84 MAPT (0.73) ALDH1A1MAPTCYP3A4CYP2C9PKM
SCHEMBL77739 0.83 KMT2A (0.73) ALDH1A1MAPTCYP3A4CYP2C9PKM
SCHEMBL21667263 0.80 MEN1 (0.50) ALDH1A1MAPTCYP3A4CYP2C9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1690 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421264-B2 Compounds and methods for the treatment of pathogenic Neisseria INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2025-09-23 US claimed
EP-4320094-A1 NOVEL MODULATORS OF THE MELATONIN RECEPTORS AS WELL AS METHOD OF MANUFACTURE AND USES THEREOF Cosmas Therapeutics Development Inc. (CA) 2024-02-14 EP claimed
WO-2022213195-A1 NOVEL MODULATORS OF THE MELATONIN RECEPTORS AS WELL AS METHOD OF MANUFACTURE AND USES THEREOF COSMAS THERAPEUTICS DEVELOPMENT INC. (CA) 2022-10-13 WO claimed
US-20220089626-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF PATHOGENIC NEISSERIA INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2022-03-24 US claimed
WO-2020051701-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF PATHOGENIC NEISSERIA INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2020-03-19 WO claimed
WO-2019169478-A1 TREATMENT OF PROTEIN AGGREGATION DISEASES USING N,N,N-TRIMETHYLCHITOSAN OVENSA INC. (CA) 2019-09-12 WO claimed
CN-105640890-A Sparingly soluble active component particle, particle preparation and preparation method thereof 华东理工大学 2016-06-08 CN claimed
CN-103565814-B The pharmaceutical composition that prevention and therapy intracranial pressure increases 和光学 2016-06-08 CN claimed
CN-103613527-B N, N-substituted 3-aminopyrrolidine compounds useful as monoamine reuptake inhibitors OTSUKA PHARMACEUTICAL CO.,LTD. (JP) 2016-02-24 CN claimed
CN-204676017-U A kind of phenylethyl barbituric acid crude product centrifugal device JINGHUA PHARMACEUTICAL GROUP NANTONG CO LTD 2015-09-30 CN claimed
EP-1448528-A2 PREPARATION OF PHARMACEUTICAL SALTS OF 4((Z)-(4-BROMOPHENYL)(ETHOXYIMINO)METHYL)-1'-((2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL)CARBONYL)-4'-METHYL-1,4'BIPIPERIDINE AS CCR5-ANTAGONISTS FOR THE TREATMENT OF AIDS AND RELATED HIV INFECTIONS SCHERING CORPORATION (US) 2004-08-25 EP claimed
CN-1157365-C Monoamine uptake inhibitors for the treatment of CNS disorders �Ʒ� 2004-07-14 CN claimed
CN-1449416-A Functionalized polymeric media for separation of analytes MALLINCKRODT INC (US) 2003-10-15 CN claimed
WO-2003066593-A2 PREPARATION OF PHARMACEUTICAL SALTS OF 4 ( (Z) - (4-BROMOPHENYL) (ETHOXYIMINO) METHYL )-1'-( (2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL) CARBONYL) -4'-METHYL-1,4' BIPIPERIDINE AS CCR5-ANTAGONISTS FOR THE TREATMENT OF AIDS AND RELATED HIV INFECTIONS SCHERING CORPORATION (US) 2003-08-14 WO claimed
US-20030144510-A1 receptor which are useful for the treatment of AIDS and related HIV infections, including the compound of Formula I. CCR-5 receptors have also been reported to mediate cell transfer in inflammatory diseases such as arthritis, SCHERING CORPORATION 2003-07-31 US claimed
US-20030139446-A1 Preparation of pharmaceutical salts SCHERING CORPORATION 2003-07-24 US claimed
WO-2003048153-A1 PROCESS FOR THE PREPARATION OF COMPOSITIONS HAVING AN INCREASED AMOUNT OF PHARMACEUTICALLY ACTIVE SALTS OF ROTAMERS SCHERING CORPORATION (US) 2003-06-12 WO claimed
CN-1353719-A Novel phosphorus-containing prodrugs METABASIS THERAPEUTICS INC (US) 2002-06-12 CN claimed
CN-1341094-A Monoamine reuptake inhibitors for treatment of CNS disorders PFIZER PROD INC (US) 2002-03-20 CN claimed
EP-0339054-B1 MIXTURE OF SUBSTANCES FOR STABILYZING METABOLISM BILAS ANDOR (AT) 1994-07-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139446-A1 Preparation of pharmaceutical salts PKD1, REN, ADCYAP1R1 ALDH1A1 1255/4885MAPT 2771/4885CYP3A4 589/4885
US-20220089626-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF PATHOGENIC NEISSERIA NMBR, MLEC, BPGM ALDH1A1 2797/4885MAPT 2341/4885CYP3A4 681/4885
US-20030144510-A1 receptor which are useful for the treatment of AIDS and related HIV infections, including the compound of Formula I. CCR-5 receptors have also been reported to mediate cell transfer in inflammatory diseases such as arthritis, CCR1, CCR5, CCR6 ALDH1A1 845/4885MAPT 4014/4885CYP3A4 2970/4885
US-12421264-B2 Compounds and methods for the treatment of pathogenic Neisseria NMBR, MLEC, BPGM ALDH1A1 2797/4885MAPT 2341/4885CYP3A4 681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.