Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2163425 | 0.85 | KMT2A (0.58) | HPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6307030 | 0.83 | KMT2A (0.39) | MAPTRAB9AHPGDLMNANPSR1 | |
| SCHEMBL18985150 | 0.81 | CA1 (0.58) | MAPTRAB9APOLBSTSSMN1; SMN2 | |
| SCHEMBL2099038 | 0.80 | ALDH1A1 (0.42) | MAPTRAB9AHPGDLMNAL3MBTL1 | |
| SCHEMBL17070018 | 0.80 | ELANE (0.58) | RAB9AHPGDNPSR1GAASTS | |
| SCHEMBL2099154 | 0.80 | ABCB1 (0.48) | MAPTRAB9AHPGDPOLBL3MBTL1 | |
| SCHEMBL19886788 | 0.80 | LMNA (0.55) | MAPTRAB9ALMNANPSR1SMN1; SMN2 | |
| SCHEMBL2099644 | 0.79 | GSK3B (0.59) | NPC1 | |
| SCHEMBL29676430 | 0.79 | ALDH5A1 (0.47) | MAPTRAB9AHPGDLMNAPOLB | |
| SCHEMBL4222501 | 0.78 | PPARG (0.41) | MAPTRAB9AHPGDPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260138977-A1 | MODULATORS OF BETA CATENIN AND USES THEREOF | DEWPOINT THERAPEUTICS INC (US) | 2026-05-21 | — | — | US | disclosed |
| US-12612396-B1 | Modulators of beta catenin and uses thereof | DEWPOINT THERAPEUTICS, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| CN-114516789-B | Cyclopropenones micromolecule compound and synthetic method and application thereof | 暨南大学 | 2023-12-05 | — | — | CN | disclosed |
| US-8163770-B2 | Benzoxathiin derivative | MSD. K. K. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20100168156-A1 | Novel Benzoxathiine Derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-07-01 | — | — | US | disclosed |
| US-20090131397-A1 | ESTROGEN MODULATORS | PFIZER INC. | 2009-05-21 | — | — | US | disclosed |
| US-20090131397-A1 | ESTROGEN MODULATORS | PFIZER INC. | 2009-05-21 | — | — | US | disclosed |
| US-7470715-B2 | Estrogen modulators | PFIZER INC. (US) | 2008-12-30 | — | — | US | disclosed |
| US-7470715-B2 | Estrogen modulators | PFIZER INC. (US) | 2008-12-30 | — | — | US | disclosed |
| EP-1966170-A2 | ESTROGEN MODULATORS | Pfizer Products Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| EP-1944301-A1 | NOVEL BENZOXATHIIN DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007072164-A2 | ESTROGEN MODULATORS | PFIZER PRODUCTS INC. (US) | 2007-06-28 | — | — | WO | disclosed |
| US-20070149564-A1 | ESTROGEN MODULATORS | PFIZER INC. (US) | 2007-06-28 | — | — | US | disclosed |
| US-20070149564-A1 | ESTROGEN MODULATORS | PFIZER INC. (US) | 2007-06-28 | — | — | US | disclosed |
| WO-1999064041-A9 | MULTIBINDING AGENTS THAT MODULATE NMDA RECEPTORS | ADVANCED MEDICINE INC (US) | 2001-05-31 | — | — | WO | disclosed |
| EP-1100519-A1 | MULTIBINDING AGENTS THAT MODULATE NMDA RECEPTORS | Advanced Medicine, Inc. (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-1999064041-A1 | MULTIBINDING AGENTS THAT MODULATE NMDA RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168156-A1 | Novel Benzoxathiine Derivative | XDH, GPR119, BRIX1 | MAPT 4652/4885RAB9A 3100/4885HPGD 3172/4885 |
| US-12612396-B1 | Modulators of beta catenin and uses thereof | CTNNB1, CTNND1, CTNNA1 | MAPT 113/4885RAB9A 445/4885HPGD 3296/4885 |
| US-20090131397-A1 | ESTROGEN MODULATORS | ESR2, GPER1, ESR1 | MAPT 3878/4885RAB9A 4193/4885HPGD 327/4885 |
| US-20260138977-A1 | MODULATORS OF BETA CATENIN AND USES THEREOF | CTNNB1, CTNND1, CTNNA1 | MAPT 113/4885RAB9A 445/4885HPGD 3296/4885 |
| US-20070149564-A1 | ESTROGEN MODULATORS | ESR2, GPER1, ESR1 | MAPT 3878/4885RAB9A 4193/4885HPGD 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.