Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21020813 | 0.75 | ALKBH3 (0.36) | ALDH1A1TDP1CYP3A4TP53ALKBH3 | |
| SCHEMBL2032766 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TDP1CYP3A4TP53TSHR | |
| SCHEMBL1033015 | 0.72 | CD44 (0.41) | ALDH1A1TDP1CYP1A1CYP1A2CYP3A4 | |
| SCHEMBL10343150 | 0.72 | PLA2G7 (0.47) | ALDH1A1TDP1CYP1A2CYP3A4TP53 | |
| SCHEMBL20076595 | 0.71 | BRD4 (0.40) | ALDH1A1TDP1CYP3A4TP53PLA2G7 | |
| SCHEMBL22232130 | 0.69 | TDP1 (0.34) | ALDH1A1TDP1CYP1A1CYP1A2CYP3A4 | |
| SCHEMBL19857180 | 0.68 | METAP2 (0.40) | ALDH1A1TDP1CYP1A1CYP1A2CYP3A4 | |
| SCHEMBL21021735 | 0.68 | PLA2G7 (0.49) | ALDH1A1CYP3A4TP53PLA2G7TSHR | |
| SCHEMBL21022263 | 0.67 | TDP1 (0.39) | ALDH1A1TDP1CYP3A4TP53TSHR | |
| SCHEMBL25530236 | 0.67 | PLA2G7 (0.40) | ALDH1A1TP53PLA2G7ALKBH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |