Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1069873 | 0.80 | SHBG (0.35) | SHBGALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL28097624 | 0.79 | SHBG (0.46) | SHBGALDH1A1CYP3A4CYP2C19EPHX1 | |
| SCHEMBL16849192 | 0.78 | SHBG (0.37) | SHBGALDH1A1CYP3A4CYP2C19EPHX1 | |
| SCHEMBL27735555 | 0.75 | ALDH1A1 (0.31) | ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL29140266 | 0.75 | SHBG (0.56) | SHBGEPHX1KDM4ETP53 | |
| SCHEMBL9135907 | 0.74 | TP53 (0.37) | SHBGALDH1A1CYP3A4CYP2C19EPHX1 | |
| SCHEMBL28090709 | 0.73 | SHBG (0.35) | SHBGALDH1A1CYP3A4CYP2C19EPHX1 | |
| SCHEMBL28122488 | 0.73 | SHBG (0.54) | SHBGALDH1A1EPHX1KDM4ETP53 | |
| SCHEMBL20857211 | 0.71 | APLNR (0.32) | SHBGALDH1A1CYP3A4CYP2C19EPHX1 | |
| SCHEMBL21938074 | 0.71 | SHBG (0.52) | SHBGALDH1A1EPHX1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | PHENEX PHARMACEUTICALS AG (DE) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | RORA, RORB, RORC | SHBG 567/4885ALDH1A1 671/4885CYP3A4 836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.