Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 5/20 | 0.38 |
| ▸ | FABP4 | P15090 | 4/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16849173 | 0.89 | CCR8 (0.39) | BRD4CCR8FABP4FABP5CTSS | |
| SCHEMBL16852627 | 0.83 | BRD4 (0.47) | BRD4CCR8FABP4CTSSCTSK | |
| SCHEMBL21028150 | 0.81 | BRD4 (0.51) | BRD4CCR8FABP4CTSSCTSK | |
| SCHEMBL18077846 | 0.81 | BRD4 (0.45) | BRD4CCR8FABP4CTSSCTSK | |
| SCHEMBL15549189 | 0.81 | FABP4 (0.47) | BRD4FABP4FABP5CTSSCTSK | |
| SCHEMBL16849852 | 0.80 | PARG (0.45) | CCR8FABP4FABP5ALDH1A1LMNA | |
| SCHEMBL16849171 | 0.76 | PARG (0.47) | CCR8FABP4FABP5CTSSCTSK | |
| SCHEMBL15549456 | 0.75 | BRD4 (0.42) | BRD4CTSSCTSKHSD11B1 | |
| SCHEMBL16849175 | 0.74 | ALOX5AP (0.41) | CCR8FABP4FABP5ALDH1A1LMNA | |
| SCHEMBL16849106 | 0.72 | ALDH1A1 (0.54) | CCR8FABP4FABP5ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | PHENEX PHARMACEUTICALS AG (DE) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | RORA, RORB, RORC | BRD4 982/4885CCR8 1015/4885FABP4 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.