Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 10/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 7/20 | 0.38 |
| ▸ | CTSK | P43235 | 7/20 | 0.38 |
| ▸ | CTSL | P07711 | 6/20 | 0.36 |
| ▸ | CTSB | P07858 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16852622 | 0.84 | PARG (0.47) | PARGRORCRORBCTSSCTSK | |
| SCHEMBL21028197 | 0.83 | PARG (0.40) | PARGRORCRORBCTSSCTSK | |
| SCHEMBL16819769 | 0.81 | PARG (0.47) | PARGRORCRORBCTSSCTSK | |
| SCHEMBL18077845 | 0.81 | PARG (0.47) | PARGRORCRORBCTSSCTSK | |
| SCHEMBL16849171 | 0.81 | PARG (0.47) | PARGRORCRORBCTSSCTSK | |
| SCHEMBL12506324 | 0.78 | PARG (0.49) | PARGRORCRORB | |
| SCHEMBL21028150 | 0.75 | BRD4 (0.51) | CTSSCTSKBRD4 | |
| SCHEMBL28200512 | 0.70 | PARG (0.64) | PARGCTSSCTSKCTSLCTSB | |
| SCHEMBL7791002 | 0.67 | TTR (0.47) | — | |
| SCHEMBL4642257 | 0.67 | LDHA (0.36) | CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | PHENEX PHARMACEUTICALS AG (DE) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | RORA, RORB, RORC | PARG 4878/4885RORC 3/4885RORB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.