Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 4/20 | 0.58 |
| ▸ | CASP3 | P42574 | 5/20 | 0.49 |
| ▸ | G6PD | P11413 | 4/20 | 0.49 |
| ▸ | PMM2 | O15305 | 3/20 | 0.46 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621565 | 0.98 | MPI (0.57) | MPICASP3G6PDPMM2PHOSPHO1 | |
| SCHEMBL28457777 | 0.93 | CASP3 (0.52) | MPICASP3G6PDPMM2PHOSPHO1 | |
| SCHEMBL30434260 | 0.93 | CASP3 (0.52) | MPICASP3G6PDPMM2PHOSPHO1 | |
| SCHEMBL21033021 | 0.85 | CASP3 (0.45) | MPICASP3G6PDPMM2PHOSPHO1 | |
| SCHEMBL21033024 | 0.85 | CASP3 (0.45) | MPICASP3G6PDPMM2PHOSPHO1 | |
| SCHEMBL11533924 | 0.82 | CASP3 (0.46) | MPICASP3G6PDHPGDRAB9A | |
| SCHEMBL787281 | 0.78 | MPI (0.64) | MPICDK4 | |
| SCHEMBL8625827 | 0.75 | HPGD (0.63) | KDM4EALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL30122754 | 0.75 | CASP3 (0.51) | MPICASP3G6PDPMM2PHOSPHO1 | |
| SCHEMBL787130 | 0.74 | MPI (1.00) | MPIG6PDPMM2PHOSPHO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053236-B2 | Substituted isoselenazolone anti-infective, anti-inflammatory, anti-cancer, cytoprotective, neuroprotective, and anti-oxidant agents | THE UNIVERSITY OF TOLEDO (US) | 2021-07-06 | — | — | US | disclosed |
| US-20190161482-A1 | SUBSTITUTED ISOSELENAZOLONE ANTI-INFECTIVE, ANTI-INFLAMMATORY, ANTI-CANCER, CYTOPROTECTIVE, NEUROPROTECTIVE, AND ANTI-OXIDANT AGENTS | THE UNIVERSITY OF TOLEDO (US) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053236-B2 | Substituted isoselenazolone anti-infective, anti-inflammatory, anti-cancer, cytoprotective, neuroprotective, and anti-oxidant agents | AIFM1, HSPE1, COX15 | MPI 1957/4885CASP3 10/4885G6PD 852/4885 |
| US-20190161482-A1 | SUBSTITUTED ISOSELENAZOLONE ANTI-INFECTIVE, ANTI-INFLAMMATORY, ANTI-CANCER, CYTOPROTECTIVE, NEUROPROTECTIVE, AND ANTI-OXIDANT AGENTS | AIFM1, HSPE1, COX15 | MPI 1957/4885CASP3 10/4885G6PD 852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.