Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 6/20 | 0.45 |
| ▸ | G6PD | P11413 | 5/20 | 0.45 |
| ▸ | MPI | P34949 | 5/20 | 0.45 |
| ▸ | PMM2 | O15305 | 4/20 | 0.42 |
| ▸ | PHOSPHO1 | Q8TCT1 | 3/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30434260 | 0.92 | CASP3 (0.52) | CASP3G6PDMPIPMM2PHOSPHO1 | |
| SCHEMBL28457777 | 0.92 | CASP3 (0.52) | CASP3G6PDMPIPMM2PHOSPHO1 | |
| SCHEMBL21033019 | 0.85 | MPI (0.58) | CASP3G6PDMPIPMM2PHOSPHO1 | |
| SCHEMBL8621565 | 0.84 | MPI (0.57) | CASP3G6PDMPIPMM2PHOSPHO1 | |
| SCHEMBL21033021 | 0.81 | CASP3 (0.45) | CASP3G6PDMPIPMM2PHOSPHO1 | |
| SCHEMBL11533924 | 0.73 | CASP3 (0.46) | CASP3G6PDMPIHPGDRAB9A | |
| SCHEMBL30122754 | 0.71 | CASP3 (0.51) | CASP3G6PDMPIPMM2PHOSPHO1 | |
| SCHEMBL4427275 | 0.68 | G6PD (0.48) | CASP3G6PDMPIPMM2PHOSPHO1 | |
| SCHEMBL22297084 | 0.68 | CASP3 (0.47) | CASP3G6PDMPIPMM2PHOSPHO1 | |
| SCHEMBL21687108 | 0.68 | CRBN (0.56) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190161482-A1 | SUBSTITUTED ISOSELENAZOLONE ANTI-INFECTIVE, ANTI-INFLAMMATORY, ANTI-CANCER, CYTOPROTECTIVE, NEUROPROTECTIVE, AND ANTI-OXIDANT AGENTS | THE UNIVERSITY OF TOLEDO (US) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190161482-A1 | SUBSTITUTED ISOSELENAZOLONE ANTI-INFECTIVE, ANTI-INFLAMMATORY, ANTI-CANCER, CYTOPROTECTIVE, NEUROPROTECTIVE, AND ANTI-OXIDANT AGENTS | AIFM1, HSPE1, COX15 | CASP3 10/4885G6PD 852/4885MPI 1957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.