Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035075 | 0.90 | MMP13 (0.45) | GPR119MMP1MMP9MMP13MMP3 | |
| SCHEMBL21035099 | 0.81 | GPR119 (0.37) | GPR119MMP1MMP9MMP13MMP3 | |
| SCHEMBL21035341 | 0.73 | ACACB (0.42) | GPR119MMP1MMP9MMP13ADAM17 | |
| SCHEMBL21035472 | 0.72 | MMP1 (0.49) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL21035536 | 0.72 | ACACB (0.41) | GPR119MMP1MMP9MMP13ADAM17 | |
| SCHEMBL21035393 | 0.72 | ACACB (0.41) | GPR119MMP1MMP9MMP13ADAM17 | |
| SCHEMBL21034927 | 0.72 | ACACB (0.42) | GPR119MMP1MMP9MMP13ADAM17 | |
| SCHEMBL21035598 | 0.72 | MMP1 (0.43) | GPR119MMP1MMP9MMP13MMP3 | |
| SCHEMBL21035593 | 0.71 | MMP1 (0.46) | GPR119MMP1MMP9MMP13MMP3 | |
| SCHEMBL21035359 | 0.68 | MMP1 (0.52) | MMP1MMP9MMP13MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |