Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.46 |
| ▸ | MMP13 | P45452 | 8/20 | 0.46 |
| ▸ | MMP9 | P14780 | 5/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.46 |
| ▸ | MMP3 | P08254 | 4/20 | 0.44 |
| ▸ | MMP7 | P09237 | 3/20 | 0.44 |
| ▸ | GHSR | Q92847 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035359 | 0.81 | MMP1 (0.52) | MMP1MMP13MMP9ADAM17MMP3 | |
| SCHEMBL21035075 | 0.79 | MMP13 (0.45) | MMP1MMP13MMP9ADAM17MMP3 | |
| SCHEMBL21035100 | 0.71 | GPR119 (0.39) | MMP1MMP13MMP9ADAM17MMP3 | |
| SCHEMBL21035424 | 0.70 | GHSR (0.40) | MMP1ADAM17GHSRKMT2AMEN1 | |
| SCHEMBL21035574 | 0.69 | MMP13 (0.53) | MMP1MMP13MMP9ADAM17MMP3 | |
| SCHEMBL21035334 | 0.67 | ADAM17 (0.55) | MMP1MMP13ADAM17MMP3MMP7 | |
| SCHEMBL21035084 | 0.67 | ADAM17 (0.55) | MMP1MMP13ADAM17MMP3MMP7 | |
| SCHEMBL21035416 | 0.67 | ADAM17 (0.55) | MMP1MMP13ADAM17MMP3MMP7 | |
| SCHEMBL21035122 | 0.67 | ADAM17 (0.55) | MMP1MMP13ADAM17MMP3MMP7 | |
| SCHEMBL21035124 | 0.67 | ADAM17 (0.55) | MMP1MMP13ADAM17MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |