Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31022115 | 0.68 | — | — | |
| SCHEMBL16168626 | 0.60 | RAB9A (0.41) | MAPTKDM4EALDH1A1KMT2ANPC1 | |
| SCHEMBL21037023 | 0.57 | MAPT (0.61) | MAPTKDM4EHTTALDH1A1MEN1 | |
| SCHEMBL21297591 | 0.56 | FAAH (0.44) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10177473 | 0.55 | ALDH1A1 (0.53) | MAPTKDM4EHTTALDH1A1MEN1 | |
| SCHEMBL1342671 | 0.55 | ALDH1A1 (0.53) | MAPTKDM4EHTTALDH1A1MEN1 | |
| SCHEMBL1342675 | 0.55 | ALDH1A1 (0.53) | MAPTKDM4EHTTALDH1A1MEN1 | |
| SCHEMBL15660986 | 0.55 | MAPT (0.61) | MAPTKDM4EHTTALDH1A1MEN1 | |
| SCHEMBL21160734 | 0.55 | MAPT (0.59) | MAPTKDM4EHTTALDH1A1MEN1 | |
| SCHEMBL11213022 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489324-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | East China University of Science and Technology (CN) | 2019-05-29 | — | — | EP | disclosed |