Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | FSCN1 | Q16658 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21042787 | 0.80 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2MAPTHTTP2RX7 | |
| SCHEMBL16593198 | 0.78 | CHRM1 (0.63) | — | |
| SCHEMBL21043066 | 0.75 | POLB (0.69) | POLBL3MBTL1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL16628330 | 0.74 | CHRM1 (0.43) | POLBL3MBTL1ALDH1A1SMN1; SMN2FSCN1 | |
| SCHEMBL21042584 | 0.74 | POLB (0.42) | POLBL3MBTL1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL19997556 | 0.73 | RPS6KB1 (0.42) | POLBL3MBTL1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL21043472 | 0.71 | NR3C1 (0.38) | POLBL3MBTL1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL16628327 | 0.70 | CHRM1 (0.63) | — | |
| SCHEMBL16593288 | 0.69 | CHRM1 (0.60) | — | |
| SCHEMBL22001751 | 0.68 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1SMN1; SMN2HTTCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-A1 | 4-AZAINDOLE DERIVATIVES | Eisai R&D Management Co., Ltd. (JP) | 2019-05-29 | — | — | EP | disclosed |