Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19997529 | 0.88 | ADRA1D (0.48) | LMNACHRM1ADRA1D | |
| SCHEMBL16628330 | 0.85 | CHRM1 (0.43) | L3MBTL1KMT2AMEN1CHRM1ALDH1A1 | |
| SCHEMBL21043053 | 0.85 | CHRM1 (0.43) | L3MBTL1CHRM1ADRA1D | |
| SCHEMBL21043062 | 0.84 | NNMT (0.42) | CHRM1 | |
| SCHEMBL16628262 | 0.83 | NPC1 (0.47) | LMNAL3MBTL1KMT2AMEN1CHRM1 | |
| SCHEMBL19997556 | 0.74 | RPS6KB1 (0.42) | L3MBTL1KMT2AMEN1ADRA1DALDH1A1 | |
| SCHEMBL19997557 | 0.73 | CCNC (0.41) | L3MBTL1ADRA1D | |
| SCHEMBL21042584 | 0.72 | POLB (0.42) | L3MBTL1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3487723 | 0.71 | ADRA1D (0.74) | ADRA1D | |
| SCHEMBL16628260 | 0.71 | CHRM1 (0.46) | CHRM1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-A1 | 4-AZAINDOLE DERIVATIVES | Eisai R&D Management Co., Ltd. (JP) | 2019-05-29 | — | — | EP | disclosed |