Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.33 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19997529 | 0.89 | ADRA1D (0.48) | CHRM1P2RX7ADRA1DTDP1PARP1 | |
| SCHEMBL16628330 | 0.88 | CHRM1 (0.43) | CHRM1P2RX7L3MBTL1SCDSMN1; SMN2 | |
| SCHEMBL16628262 | 0.86 | NPC1 (0.47) | CHRM1P2RX7ADRA1DKDM4EL3MBTL1 | |
| SCHEMBL21043057 | 0.85 | LMNA (0.47) | CHRM1ADRA1DL3MBTL1 | |
| SCHEMBL21043062 | 0.81 | NNMT (0.42) | CHRM1P2RX7SIRT3TDP1 | |
| SCHEMBL16628266 | 0.78 | LMNA (0.49) | P2RX7SMN1; SMN2 | |
| SCHEMBL21042584 | 0.75 | POLB (0.42) | KDM4EL3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL19997556 | 0.74 | RPS6KB1 (0.42) | ADRA1DKDM4EL3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL19997557 | 0.73 | CCNC (0.41) | ADRA1DKDM4EL3MBTL1PARP1 | |
| SCHEMBL21043478 | 0.71 | PDE2A (0.43) | CHRM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-A1 | 4-AZAINDOLE DERIVATIVES | Eisai R&D Management Co., Ltd. (JP) | 2019-05-29 | — | — | EP | disclosed |