Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 3/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21049817 | 0.89 | HRH3 (0.33) | HRH3SMN1; SMN2CYP3A4 | |
| SCHEMBL21049808 | 0.79 | LTA4H (0.46) | HRH3ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL21049804 | 0.77 | ALDH1A1 (0.56) | HRH3ALDH1A1LMNASMN1; SMN2USP2 | |
| SCHEMBL21049834 | 0.74 | EBP (0.47) | HRH3HTTSMN1; SMN2KMT2ALTA4H | |
| SCHEMBL21049819 | 0.73 | HRH3 (0.58) | HRH3ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL21049816 | 0.73 | L3MBTL1 (0.35) | HRH3ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL13303281 | 0.69 | LTA4H (0.57) | TSHRLTA4HGAARAB9ACYP3A4 | |
| SCHEMBL1586530 | 0.68 | KDM4E (0.54) | HRH3ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL3267040 | 0.68 | SMN1; SMN2 (0.56) | ALDH1A1LMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL8140756 | 0.67 | NPC1 (0.47) | ALDH1A1SMN1; SMN2LTA4HGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707125-A1 | CAFFEIC ACID DERIVATIVES FOR TREATING HYPERPROLIFERATIVE DISEASES | Board Of Regents, The University Of Texas System (US) | 2020-09-16 | — | — | EP | disclosed |
| US-10703721-B2 | Caffeic acid derivatives and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-07-07 | — | — | US | disclosed |
| US-20190177276-A1 | CAFFEIC ACID DERIVATIVES AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2019-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10703721-B2 | Caffeic acid derivatives and uses thereof | GLS, GLS2, NCOA2 | HRH3 3249/4885ALDH1A1 204/4885LMNA 3017/4885 |
| US-20190177276-A1 | CAFFEIC ACID DERIVATIVES AND USES THEREOF | GLS, GLS2, NCOA2 | HRH3 3249/4885ALDH1A1 204/4885LMNA 3017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.