SCHEMBL21058347

SCHEMBL21058347

CCCC(=O)N[C@H]1C(O)O[C@H](COC(=O)C(C)c2ccc(CC(C)C)cc2)[C@@H](O)[C@@H]1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 8/20 0.43
▸ PTGS1 P23219 4/20 0.43
▸ CXCR1 P25024 3/20 0.43
▸ CXCR2 P25025 3/20 0.43
▸ LMNA P02545 2/20 0.43
▸ CYP2C9 P11712 2/20 0.43
▸ AKR1C3 P42330 2/20 0.43
▸ ALB P02768 1/20 0.43
▸ ESR1 P03372 1/20 0.43
▸ ALOX5 P09917 1/20 0.43
▸ RARB P10826 1/20 0.43
▸ ADRB3 P13945 1/20 0.43
▸ NFKB1 P19838 1/20 0.43
▸ HTR2A P28223 1/20 0.43
▸ NR1I3 Q14994 1/20 0.43
▸ SLC22A6 Q4U2R8 1/20 0.43
▸ CXCL8 P10145 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ AKR1C2 P52895 1/20 0.43
▸ BLM P54132 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25957461 0.92 SLC2A1 (0.36) PTGS2
SCHEMBL21138772 0.91 PTGS2 (0.42) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL25957583 0.89 PTGS2 (0.37) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL23104795 0.84 MAPK1 (0.40) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL21058392 0.84 MAPK1 (0.40) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL25835021 0.84 MAPK1 (0.40) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL25957856 0.83 ACACB (0.34) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL21138771 0.82 PTGS2 (0.42) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL25837056 0.82 PTGS2 (0.42) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL21137857 0.80 HK1 (0.41) PTGS1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552823-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2026-02-17 — — US disclosed
US-20250353870-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2025-11-20 — — US disclosed
US-12312378-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2025-05-27 — — US disclosed
US-20240051982-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2024-02-15 — — US disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
CN-115594724-A Glucosamine derivatives for preventing or treating joint diseases 润佳(苏州)医药科技有限公司(CN) 2023-01-13 — — CN disclosed
CN-115215911-A Glucosamine derivative, composition thereof and medical application thereof 润佳(苏州)医药科技有限公司 2022-10-21 — — CN disclosed
CN-111971290-B Glucosamine derivatives for preventing or treating joint diseases 润佳(苏州)医药科技有限公司 2022-10-14 — — CN disclosed
CN-109929001-B Glucosamine derivative, composition thereof and medical application thereof 润佳(苏州)医药科技有限公司 2022-07-08 — — CN disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
CN-111971290-A Glucosamine derivatives for preventing or treating joint diseases 润佳(苏州)医药科技有限公司 2020-11-20 — — CN disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353870-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA PTGS2 702/4885PTGS1 313/4885CXCR1 2313/4885
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA PTGS2 648/4885PTGS1 271/4885CXCR1 2674/4885
US-20240051982-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, FUT6 PTGS2 443/4885PTGS1 180/4885CXCR1 3205/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA PTGS2 648/4885PTGS1 271/4885CXCR1 2674/4885
US-12552823-B2 Glucosamine derivatives and pharmaceutical uses thereof SOST, FUT6, SLC5A1 PTGS2 1046/4885PTGS1 592/4885CXCR1 3073/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA PTGS2 702/4885PTGS1 313/4885CXCR1 2313/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA PTGS2 702/4885PTGS1 313/4885CXCR1 2313/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA PTGS2 702/4885PTGS1 313/4885CXCR1 2313/4885
US-12312378-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, FUT6 PTGS2 443/4885PTGS1 180/4885CXCR1 3205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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