Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | VDR | P11473 | 4/20 | 0.42 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155060 | 1.00 | HMGCR (0.56) | HMGCRLCKPTGS1PTGS2VDR | |
| SCHEMBL2106841 | 1.00 | HMGCR (0.56) | HMGCRLCKPTGS1PTGS2VDR | |
| SCHEMBL6155055 | 1.00 | HMGCR (0.56) | HMGCRLCKPTGS1PTGS2VDR | |
| SCHEMBL2107875 | 0.99 | HMGCR (0.57) | HMGCRLCKPTGS1PTGS2VDR | |
| SCHEMBL2107876 | 0.99 | HMGCR (0.57) | HMGCRLCKPTGS1PTGS2VDR | |
| SCHEMBL2108149 | 0.93 | HMGCR (0.57) | HMGCRLCKAKR1B10AKR1B1ABL1 | |
| SCHEMBL2106285 | 0.93 | HMGCR (0.57) | HMGCRLCKAKR1B10AKR1B1ABL1 | |
| SCHEMBL2106283 | 0.93 | HMGCR (0.57) | HMGCRLCKAKR1B10AKR1B1ABL1 | |
| SCHEMBL2108148 | 0.93 | HMGCR (0.57) | HMGCRLCKAKR1B10AKR1B1ABL1 | |
| SCHEMBL6154965 | 0.93 | HMGCR (0.52) | HMGCRLCKPTGS1PTGS2VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | claimed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | claimed |
| EP-2879656-B2 | DYE COMPOSITION IN CREAM FORM COMPRISING AT LEAST ONE OIL AND LITTLE OR NO SOLID FATTY ALCOHOL, DYEING PROCESS AND SUITABLE DEVICE | OREAL (FR) | 2024-07-17 | — | — | EP | disclosed |
| US-11730682-B2 | Self-standing cosmetic sheet | L'OREAL (FR) | 2023-08-22 | — | — | US | disclosed |
| EP-2879649-B2 | DYEING COMPOSITION COMPRISING AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE OXIDIZING AGENT AND AT LEAST ONE NON-IONIC, ANIONIC AND AMPHOTERIC SURFACTANT | OREAL (FR) | 2022-08-24 | — | — | EP | disclosed |
| EP-2836187-B1 | SELF-STANDING COSMETIC SHEET | OREAL (FR) | 2021-12-08 | — | — | EP | disclosed |
| EP-2879656-B1 | DYE COMPOSITION IN CREAM FORM COMPRISING AT LEAST ONE OIL AND LITTLE OR NO SOLID FATTY ALCOHOL, DYEING PROCESS AND SUITABLE DEVICE | OREAL (FR) | 2019-05-29 | — | — | EP | disclosed |
| US-10226411-B2 | Dyeing composition comprising a fatty substance, a non-ionic guar gum, an amphoteric surfactant and a non-ionic or anionic surfactant, and an oxidizing agent, dyeing process and suitable device | L'OREAL (FR) | 2019-03-12 | — | — | US | disclosed |
| US-10201483-B2 | Dye composition in cream form comprising at least one oil and little or no solid fatty alcohol, dyeing process and suitable device | L'OREAL (FR) | 2019-02-12 | — | — | US | disclosed |
| EP-2879649-B1 | DYEING COMPOSITION COMPRISING AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE OXIDIZING AGENT AND AT LEAST ONE NON-IONIC, ANIONIC AND AMPHOTERIC SURFACTANT | OREAL (FR) | 2018-11-07 | — | — | EP | disclosed |
| US-20180235849-A1 | SELF-STANDING COSMETIC SHEET | L'OREAL (FR) | 2018-08-23 | — | — | US | disclosed |
| US-20060233736-A1 | Cosmetic compositions containing mono-hydroxyl substituted amines and acid derivatives | L'OREAL (FR) | 2006-10-19 | — | — | US | disclosed |
| EP-1658838-A1 | Emulsification system for use in cosmetics | L'OREAL (FR) | 2006-05-24 | — | — | EP | disclosed |
| US-20060039936-A1 | Emulsification system for use in cosmetics | L'OREAL (FR) | 2006-02-23 | — | — | US | disclosed |
| US-20050169945-A1 | Composition for protecting keratin material, process of making, uses thereof | L'OREAL (FR) | 2005-08-04 | — | — | US | disclosed |
| EP-1559398-A1 | Process for preparing a composition for the cosmetic treatment of keratinous materials on the basis of a pressurised fluid and vitamins | L'OREAL (FR) | 2005-08-03 | — | — | EP | disclosed |
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| US-20020197289-A1 | Compositions and methods for combating the appearance of ageing | L'OREAL (FR) | 2002-12-26 | — | — | US | disclosed |
| EP-1262168-A1 | Composition containing fibres to combat the skin aging process | L'OREAL (FR) | 2002-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10226411-B2 | Dyeing composition comprising a fatty substance, a non-ionic guar gum, an amphoteric surfactant and a non-ionic or anionic surfactant, and an oxidizing agent, dyeing process and suitable device | KRT18, OAT, DSG1 | HMGCR 1759/4885LCK 3149/4885PTGS1 885/4885 |
| US-20060233736-A1 | Cosmetic compositions containing mono-hydroxyl substituted amines and acid derivatives | TYR, PHOSPHO1, DDC | HMGCR 1495/4885LCK 1294/4885PTGS1 2750/4885 |
| US-20020197289-A1 | Compositions and methods for combating the appearance of ageing | CYP24A1, CYP27B1, CYP2R1 | HMGCR 283/4885LCK 4528/4885PTGS1 2838/4885 |
| US-10201483-B2 | Dye composition in cream form comprising at least one oil and little or no solid fatty alcohol, dyeing process and suitable device | KRT18, CUTA, DSG1 | HMGCR 844/4885LCK 1767/4885PTGS1 1230/4885 |
| US-20180235849-A1 | SELF-STANDING COSMETIC SHEET | CUTA, DSG1, SUCLG1 | HMGCR 565/4885LCK 2789/4885PTGS1 1771/4885 |
| US-11730682-B2 | Self-standing cosmetic sheet | CUTA, DSG1, SUCLG1 | HMGCR 565/4885LCK 2789/4885PTGS1 1771/4885 |
| US-20050169945-A1 | Composition for protecting keratin material, process of making, uses thereof | KRT18, PROC, CUTA | HMGCR 1113/4885LCK 3497/4885PTGS1 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.