Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | IDE | P14735 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412235 | 0.71 | BCHE (0.52) | LMNATDP1 | |
| SCHEMBL28166017 | 0.63 | LMNA (0.46) | LMNAG6PDIDECA2ENPP2 | |
| SCHEMBL4959356 | 0.63 | MAPK1 (0.55) | LMNATDP1G6PDIDEENPP2 | |
| SCHEMBL27891624 | 0.62 | LMNA (0.49) | LMNAENPP2AKR1C3AKR1C2 | |
| SCHEMBL10508027 | 0.61 | NOTUM (0.41) | LMNATDP1G6PDIDEDRD2 | |
| SCHEMBL22148182 | 0.59 | G6PD (0.49) | LMNAG6PDIDECA12CA1 | |
| SCHEMBL2911234 | 0.59 | SMN1; SMN2 (0.49) | LMNAG6PDIDEENPP2SLC9A1 | |
| SCHEMBL23850820 | 0.58 | RAB9A (0.70) | LMNASLC6A9TDP1 | |
| SCHEMBL31587411 | 0.58 | RAB9A (0.70) | LMNASLC6A9TDP1 | |
| SCHEMBL1381443 | 0.58 | CA2 (0.65) | CA12CA1CA2CA9ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |