Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773556 | 0.85 | CA2 (0.55) | IKBKBCHUKMKNK1MKNK2CA2 | |
| SCHEMBL4959356 | 0.85 | MAPK1 (0.55) | LMNAIKBKBCHUKBRD4MAPK1 | |
| SCHEMBL27891624 | 0.85 | LMNA (0.49) | LMNAENPP2 | |
| SCHEMBL1017780 | 0.83 | LMNA (0.61) | LMNAMAPK1ENPP2 | |
| SCHEMBL1482128 | 0.83 | LMNA (0.47) | LMNAENPP2 | |
| SCHEMBL22148182 | 0.81 | G6PD (0.49) | LMNAIKBKBCHUKBRD4CA2 | |
| SCHEMBL27462999 | 0.81 | LMNA (0.50) | LMNAENPP2 | |
| SCHEMBL2911234 | 0.81 | SMN1; SMN2 (0.49) | LMNAIKBKBCHUKSLC9A1BRD4 | |
| SCHEMBL27780444 | 0.81 | LMNA (0.42) | LMNASLC9A1ENPP2G6PDIDE | |
| SCHEMBL4369013 | 0.80 | DGAT1 (0.53) | LMNAIKBKBCHUKBRD4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103649053-B | Aminomethyl quinolone compounds | 霍夫曼-拉罗奇有限公司 | 2017-07-04 | — | — | CN | disclosed |