Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 2/20 | 0.44 |
| ▸ | CHUK | O15111 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28166017 | 0.81 | LMNA (0.46) | LMNAIKBKBCHUKENPP2G6PD | |
| SCHEMBL16990464 | 0.81 | SLC9A1 (0.44) | SMN1; SMN2SLC9A1 | |
| SCHEMBL22148182 | 0.81 | G6PD (0.49) | LMNAIKBKBCHUKENPP2G6PD | |
| SCHEMBL4369013 | 0.80 | DGAT1 (0.53) | LMNAIKBKBCHUKPDE4BBRD4 | |
| SCHEMBL2894517 | 0.80 | LMNA (0.57) | LMNA | |
| SCHEMBL17505003 | 0.80 | DGAT1 (0.53) | SLC9A1NR1H2NR1H3 | |
| SCHEMBL2911414 | 0.79 | SLC9A1 (0.42) | SMN1; SMN2SLC9A1 | |
| SCHEMBL4959356 | 0.78 | MAPK1 (0.55) | SMN1; SMN2LMNAIKBKBCHUKADRA1D | |
| SCHEMBL12505411 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAPDE4B | |
| SCHEMBL2910227 | 0.77 | ADRA1D (0.41) | IKBKBCHUKADRA1DSLC9A1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325920-B1 | N-SUBSTITUTED BENZOTHIOPHENESULFONAMIDE DERIVATIVES | TOA EIYO LTD (JP) | 2010-08-25 | — | — | EP | disclosed |
| EP-1325920-A1 | N-SUBSTITUTED BENZOTHIOPHENESULFONAMIDE DERIVATIVES | TOA EIYO LTD. (JP) | 2003-07-09 | — | — | EP | disclosed |