SCHEMBL21077039

SCHEMBL21077039

CC(C)n1c2c(-c3ccccc3)cccc2c2cccc(-c3ccccc3)c21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CDC25A P30304 4/20 0.54
▸ CDC25C P30307 4/20 0.54
▸ PDCD1 Q15116 1/20 0.39
▸ CD274 Q9NZQ7 1/20 0.39
▸ BRD4 O60885 1/20 0.38
▸ PARP1 P09874 1/20 0.36
▸ MAP4K4 O95819 1/20 0.36
▸ CSF1R P07333 1/20 0.36
▸ FGFR1 P11362 1/20 0.36
▸ PDGFRA P16234 1/20 0.36
▸ LTK P29376 1/20 0.36
▸ KDR P35968 1/20 0.36
▸ MAPK8 P45983 1/20 0.36
▸ CSNK1A1 P48729 1/20 0.36
▸ LIMK1 P53667 1/20 0.36
▸ CDK5 Q00535 1/20 0.36
▸ ACVR1 Q04771 1/20 0.36
▸ TNK2 Q07912 1/20 0.36
▸ AURKB Q96GD4 1/20 0.36
▸ CLK4 Q9HAZ1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24775177 0.90 CDC25A (0.46) CDC25ACDC25CPDCD1CD274HSD17B10
SCHEMBL21023174 0.80 CDC25A (0.50) CDC25ACDC25CPDCD1CD274BRD4
SCHEMBL14931060 0.78 HSD17B10 (0.46) PDCD1CD274BRD4MAP4K4CSF1R
SCHEMBL26237868 0.77 BCHE (0.45) CDC25ACDC25CBCHEACHEALDH1A1
SCHEMBL26237862 0.74 MEN1 (0.43) CDC25ACDC25CHSD17B10BCHEACHE
SCHEMBL26237878 0.74 MEN1 (0.49) CDC25ACDC25CBCHEACHE
SCHEMBL26256463 0.74 MAP4K4 (0.39) PDCD1CD274BRD4PARP1MAP4K4
SCHEMBL21076114 0.73 CDC25A (0.40) CDC25ACDC25CPDCD1CD274LIMK1
SCHEMBL21077138 0.73 PDCD1 (0.43) PDCD1CD274BRD4MAP4K4CSF1R
SCHEMBL14929538 0.73 PDCD1 (0.39) CDC25ACDC25CPDCD1CD274BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230303602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 — — US disclosed
US-20230284517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-07 — — US disclosed
US-20230212177-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-06 — — US disclosed
US-20230200211-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 — — US disclosed
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-01 — — US disclosed
US-20230118611-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 — — US disclosed
US-20230041530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-09 — — US disclosed
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSITY DISPLAY CORPORATION (US) 2022-12-22 — — US disclosed
US-20220069241-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-03-03 — — US disclosed
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 — — US disclosed
US-20190173020-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES Kyulux North America, Inc. 2019-06-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230284517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OCIAD1 CDC25A 4662/4885CDC25C 4735/4885PDCD1 67/4885
US-20230118611-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, NR4A1 CDC25A 4142/4885CDC25C 4436/4885PDCD1 1579/4885
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP CDC25A 3996/4885CDC25C 3814/4885PDCD1 216/4885
US-20230200211-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OPRM1, OCIAD1 CDC25A 3624/4885CDC25C 4201/4885PDCD1 537/4885
US-20220069241-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CHRM1, LBR, CNKSR1 CDC25A 2293/4885CDC25C 2149/4885PDCD1 1269/4885
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, LEF1 CDC25A 2930/4885CDC25C 3188/4885PDCD1 3200/4885
US-20230303602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 CDC25A 4219/4885CDC25C 3554/4885PDCD1 11/4885
US-20230212177-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT CRY1, CRY2, NR2E3 CDC25A 3880/4885CDC25C 3929/4885PDCD1 3835/4885
US-20190173020-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, ALDH1A2, CYBA CDC25A 1929/4885CDC25C 1203/4885PDCD1 3418/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 CDC25A 3625/4885CDC25C 3380/4885PDCD1 1357/4885
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP CDC25A 4156/4885CDC25C 4195/4885PDCD1 338/4885
US-20230041530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CHRM1 CDC25A 2693/4885CDC25C 2529/4885PDCD1 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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