SCHEMBL2107754

SCHEMBL2107754

CCN(CC)c1ccc(C(c2ccc(N(CC)CC)cc2)c2ccccc2S(=O)(=O)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
L3MBTL1 Q9Y468 4/20 0.44
HPGD P15428 3/20 0.44
HSP90AA1 P07900 2/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
CNR2 P34972 11/20 0.44
TSHR P16473 1/20 0.43
GRK6 P43250 1/20 0.42
CNR1 P21554 2/20 0.41
HSD11B1 P28845 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MAPT P10636 2/20 0.40
NOX1 Q9Y5S8 1/20 0.40
KDM4E B2RXH2 1/20 0.40
THRB P10828 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30487077 1.00 ALDH1A1 (0.44) ALDH1A1MEN1KMT2AL3MBTL1HPGD
SCHEMBL10595694 0.99 CNR2 (0.43) ALDH1A1MEN1KMT2AL3MBTL1HPGD
SCHEMBL18719294 0.90 TSHR (0.50) ALDH1A1KMT2AHPGDCNR2TSHR
SCHEMBL14107192 0.87 L3MBTL1 (0.37) ALDH1A1MEN1KMT2AL3MBTL1HPGD
SCHEMBL108903 0.87 CNR2 (0.47) CNR2TSHRCNR1
SCHEMBL1436602 0.86 CNR2 (0.47) CNR2TSHRCNR1
SCHEMBL12902083 0.84 KMT2A (0.44) ALDH1A1MEN1KMT2AL3MBTL1CNR2
SCHEMBL12659715 0.84 CNR2 (0.41) ALDH1A1MEN1KMT2AL3MBTL1HPGD
SCHEMBL8853777 0.84 THRB (0.46) ALDH1A1MEN1KMT2AHPGDCNR2
SCHEMBL13817789 0.84 L3MBTL1 (0.41) ALDH1A1MEN1KMT2AL3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0148275-B1 PROCESS FOR DECOMPOSING ASCORBIC ACID WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-02 EP claimed
EP-0148275-A1 PROCESS FOR DECOMPOSING ASCORBIC ACID WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1985-07-17 EP claimed
JP-56026199-A None JP disclosed
US-20230159444-A1 PROCESS FOR SYNTHESIZING SULFONATED TRIARYL METHANE COMPOUNDS PROVEPHARM LIFE SOLUTIONS (FR) 2023-05-25 US disclosed
US-10989714-B2 Measurement of glycoprotein ARKRAY, INC. (JP) 2021-04-27 US disclosed
US-20190137502-A1 Measurement of Glycoprotein ARKRAY, INC. (JP) 2019-05-09 US disclosed
EP-3461907-A1 MEASUREMENT OF GLYCOPROTEIN ARKRAY, Inc. (JP) 2019-04-03 EP disclosed
EP-1903069-B1 NOVEL POLYMER AND METHOD OF MEASURING CHOLESTEROL THEREWITH WAKO PURE CHEM IND LTD (JP) 2015-08-12 EP disclosed
US-8158375-B2 Polymer and method of measuring cholesterol therewith WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2012-04-17 US disclosed
EP-2239281-A2 Novel polymer and method for determining cholesterol using the same Wako Pure Chemical Industries, Ltd. (JP) 2010-10-13 EP disclosed
US-20090215097-A1 Novel Polymer and Method of Measuring Cholesterol Therewith WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2009-08-27 US disclosed
EP-0124909-B1 PROCESS FOR DETERMINING REDUCED FORM COENZYMES WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1989-02-15 EP disclosed
US-4778753-A IN PRESCENCE OF URICASE, METAL CHELATE AND ANIONIC SURFACTANT; WITHOUT COLORING INTERFERENCE WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 1988-10-18 US disclosed
US-4673635-A Triphenyl methane derivatives and method of quantitatively measuring an oxidative substance WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 1987-06-16 US disclosed
US-4613465-A HYDROGEN PEROXIDE, BODY FLUIDS, ENZYMES WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 1986-09-23 US disclosed
US-4592996-A Reacting with a peroxidase; colorimetric analysis of hydrogen peroxide produced WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1986-06-03 US disclosed
EP-0174371-A1 TRIPHENYLMETHANE DERIVATIVES AND METHOD FOR DETERMINING OXIDATIVE SUBSTANCES USING THEM AS COLOR-FORMING COMPONENT WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1986-03-19 EP disclosed
EP-0148275-A1 PROCESS FOR DECOMPOSING ASCORBIC ACID WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1985-07-17 EP disclosed
EP-0124909-A2 Process for determining reduced form coenzymes WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1984-11-14 EP disclosed
JP-S5626199-A DETERMINATION OF MINOR CONSTITUENT CONTAINED IN SERUM OR URINE FUJIREBIO INC 1981-03-13 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10989714-B2 Measurement of glycoprotein ENGASE, UGGT1, ST6GAL1 ALDH1A1 1179/4885MEN1 2371/4885KMT2A 4798/4885
US-20190137502-A1 Measurement of Glycoprotein ENGASE, UGGT1, ST6GAL1 ALDH1A1 1179/4885MEN1 2371/4885KMT2A 4798/4885
US-20230159444-A1 PROCESS FOR SYNTHESIZING SULFONATED TRIARYL METHANE COMPOUNDS SQOR, SULT1E1, TST ALDH1A1 445/4885MEN1 914/4885KMT2A 2599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.